6533b837fe1ef96bd12a2761
RESEARCH PRODUCT
Standardized Model of Ventricular Fibrillation and Advanced Cardiac Life Support in Swine
Andreas Garcia-bardonRobert RuemmlerErik K. HartmannAlexander ZiebartJens Kamufsubject
Malemedicine.medical_specialtyCardiac outputResuscitationSwineGeneral Chemical Engineeringmedicine.medical_treatmentPsychological interventionMEDLINEAdvanced Cardiac Life SupportDecarboxylationGeneral Biochemistry Genetics and Molecular Biologylaw.invention03 medical and health sciences0302 clinical medicineRandomized controlled triallawmedicineAnimals030212 general & internal medicineCardiopulmonary resuscitationCardiac OutputIntensive care medicineGeneral Immunology and Microbiologybusiness.industryGeneral NeuroscienceAdvanced cardiac life support030208 emergency & critical care medicinemedicine.diseaseCardiopulmonary ResuscitationOxygenDisease Models AnimalVentricular FibrillationVentricular fibrillationbusinessdescription
Cardiopulmonary resuscitation after cardiac arrest, independent of its origin, is a regularly encountered medical emergency in hospitals as well as preclinical settings. Prospective randomized trials in human subjects are difficult to design and ethically ambiguous, which results in a lack of evidence-based therapies. The model presented in this report represents one of the most common causes of cardiac arrests, ventricular fibrillation, in a standardized setting in a large animal model. This allows for reproducible observations and various therapeutic interventions under clinically accurate conditions, hence facilitating the generation of better evidence and eventually the potential for improved medical treatment.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2020-01-30 | Journal of Visualized Experiments |