6533b837fe1ef96bd12a33ac
RESEARCH PRODUCT
Kawasaki disease recurrence in the COVID-19 era: a systematic review of the literature
Claudia ColombaAlice Annalisa MedagliaClaudia GioèAntonio CascioLucia SiracusaSalvatore Giordanosubject
Pediatricsmedicine.medical_specialtyHeart diseaseSettore MED/17 - Malattie InfettiveDiseaseReviewMucocutaneous Lymph Node SyndromePediatricsRJ1-57003 medical and health sciences0302 clinical medicineRecurrence030225 pediatricsSars-Cov2EpidemiologymedicineHumans030212 general & internal medicineskin and connective tissue diseasesChildPandemicsbusiness.industrySARS-CoV-2Incidence (epidemiology)IncidenceInfantmedicine.diseaseSars-Cov2Coronary arteriesmedicine.anatomical_structureRecurrent Kawasaki diseaseChild PreschoolKawasaki diseaseKawasaki disease recurrenceVasculitisbusinessCovid-19Medical literaturedescription
Kawasaki disease (KD) is a vasculitis of unknown origin of small and medium caliber blood vessels, especially involving coronary arteries and is the leading cause of acquired heart disease in childhood in developed countries. Although rarely, it can recur: most recurrences occur within 2 years of the initial episode. No data are available on incidence of recurrent KD in Europe and multiple recurrences are rarely seen. We reviewed the medical literature on Kawasaki disease recurrence and reported a new case of Kawasaki disease recurrence in a child with SARS-CoV-2 infection. We believe that in our case SARS Cov2 acted as a trigger capable to determine, in a genetically susceptible individual, a second recurrence of the disease. In the Covid-19 era we affirm the importance for Kawasaki disease to be tested for SARS Cov2 infection. Supplementary Information The online version contains supplementary material available at 10.1186/s13052-021-01041-4.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2021-04-01 |