6533b838fe1ef96bd12a512d

RESEARCH PRODUCT

Biological evaluation of PLLA membranes, with different pore diameters, to stimulate cell adhesion and growth in vitro

Alberto FucarinoValerio BrucatoSalvatore MontesantoFabio BucchieriV. La Carrubba

subject

chemistry.chemical_classificationMaterials scienceRegeneration (biology)DiffusionPhase separationtechnology industry and agriculturepolymeric MembranePolymerPLLASolventPhysics and Astronomy (all)MembranechemistryChemical engineeringPolymer chemistryCell AdhesionCell adhesionTernary operationPorosity

description

Polymeric membranes prepared via DIPS (Diffusion Induced Phase Separation) are widely studied and utilized as scaffolds for the regeneration of tissue. In this work, poly (L)-lactide membrane are prepared through a DIPS protocol starting from a ternary solution made of polymer, dioxane (solvent) and water (non-solvent). A three-dimensional, porous and mechanically stable membrane is desirable for ingrowth of human bronchial epithelial cells. Polymeric membranes prepared via DIPS (Diffusion Induced Phase Separation) are widely studied and utilized as scaffolds for the regeneration of tissue. In this work, poly (L)-lactide membrane are prepared through a DIPS protocol starting from a ternary solution made of polymer, dioxane (solvent) and water (non-solvent). A three-dimensional, porous and mechanically stable membrane is desirable for ingrowth of human bronchial epithelial cells.

https://doi.org/10.1063/1.4937319