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RESEARCH PRODUCT

Early adolescent aggression predicts antisocial personality disorder in young adults : a population-based study

Anu RaevuoriAnu RaevuoriTellervo KorhonenAlyce M WhippKauko HeikkiläEero VuoksimaaRichard J. RoseJaakko KaprioLea Pulkkinen

subject

MaleaggressiivisuusCHILDHOODALCOHOLAntisocial personality disorderPopulation-based3124 Neurology and psychiatryCohort Studies0302 clinical medicineantisocial personality disordernuoretDevelopmental and Educational PsychologyChild and adolescent psychiatryYoung adultChildeducation.field_of_study05 social sciencesaggressionPSYCHIATRIC-DISORDERSPSYCHOPATHOLOGYOriginal ContributionGeneral Medicine16. Peace & justicePREVALENCEDiagnostic and Statistical Manual of Mental DisordersAggressionPsychiatry and Mental healthConduct disorderFemalemedicine.symptomPsychologyBEHAVIOR050104 developmental & child psychologyPsychopathologyClinical psychologypsychiatric predictionmedicine.medical_specialtyAdolescent515 PsychologyPopulationTWINNATIONAL EPIDEMIOLOGIC SURVEY03 medical and health sciencesmielenterveyshäiriötmental disordersPsychiatric predictionmedicineHumans0501 psychology and cognitive scienceseducationnuoret aikuisetAggressionAntisocial personality disorderennusteetOdds ratiomedicine.diseaseELEMENTARY-SCHOOL030227 psychiatrypopulation-basedadolescentCONDUCT DISORDERPediatrics Perinatology and Child Healthpoikkeava käyttäytyminen

description

Modestly prevalent in the general population (~ 4%), but highly prevalent in prison populations (> 40%), the diagnosis of antisocial personality disorder (ASPD) involves aggression as one of several possible criteria. Using multiple informants, we aimed to determine if general aggression, as well as direct and indirect subtypes, assessed in early adolescence (ages 12, 14) predict young adulthood ASPD in a population-based sample. Using data from a Finnish population-based longitudinal twin cohort study with psychiatric interviews available at age 22 (N = 1347), we obtained DSM-IV-based ASPD diagnoses. Aggression measures from ages 12 (parental and teacher ratings) and 14 (teacher, self, and co-twin ratings) were used to calculate odds ratios (OR) of ASPD from logistic regression models and the area under the curve (AUC) from receiver operating characteristic curve analysis. Analyses were adjusted for sex, age, and family structure. All informants’ aggression ratings were significant (p < 0.05) predictors of ASPD (OR range 1.3–1.8; AUC range 0.65–0.72). Correlations between informants ranged from 0.13 to 0.33. Models including two or more aggression ratings, particularly age 14 teacher and self ratings, more accurately predicted ASPD (AUC: 0.80; 95% confidence interval 0.73–0.87). Direct aggression rated by all informants significantly predicted ASPD (OR range 1.4–1.9), whereas only self-rated indirect aggression was significantly associated with ASPD (OR = 1.4). Across different informants, general and direct aggression at ages 12 and 14 predicted ASPD in a population-based sample. Psychiatric, social, and parenting interventions for ASPD prevention should focus on children and adolescents with high aggression levels, with an aim to gather information from multiple informants. Electronic supplementary material The online version of this article (10.1007/s00787-018-1198-9) contains supplementary material, which is available to authorized users.

yearjournalcountryeditionlanguage
2018-07-01
10.1007/s00787-018-1198-9http://hdl.handle.net/10138/300735