6533b839fe1ef96bd12a5b15
RESEARCH PRODUCT
A NONHEALING ULCER DIAGNOSED AS EXTRAMEDULLARY PLASMOCYTOMA OF THE LIMB EIGHT YEARS AFTER CARDIAC TRANSPLANTATION
T WittlingerH DariusWaltraut IbeJ MeyerM Sebastiansubject
Graft RejectionMaleImmunofixationmedicine.medical_specialtySkin NeoplasmsUrinalysisMalignancyBiopsymedicineHumansTransplantationmedicine.diagnostic_testbiologybusiness.industryLeg UlcerMiddle Agedmedicine.diseaseSurgeryTransplantationHematopoiesis ExtramedullarySerum protein electrophoresisCyclosporinebiology.proteinHeart TransplantationPlasmacytomabusinessComplicationImmunosuppressive AgentsPlasmacytomadescription
A 63-year-old man was hospitalized for a nonhealing ulcer of the left lower leg that appeared 8 years after orthotopic cardiac transplantation under immunosuppressive therapy including cyclosporine. Serum protein electrophoresis, immunofixation, and urinalysis revealed a monoclonal gammopathy IgG kappa. The final diagnosis of an extramedullary plasmocytoma was made by biopsy of the ulcer, which showed formations of plasmablastic cells. We report a rare case of extramedullary plasmocytoma as a posttransplantational malignancy.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1999-10-09 | Transplantation |