6533b839fe1ef96bd12a5b80

RESEARCH PRODUCT

Visualization of corneal vascularization in peripheral hypertrophic subepithelial corneal opacification with OCT angiography.

Walter LischVeronika Weyer-elberichJana C RiedlUrs VossmerbaeumerNorbert PfeifferAdrian GerickeJoanna Wasielica-poslednik

subject

AdultMalemedicine.medical_specialtyTime Factorsgenetic structuresFundus OculiSlit Lamp MicroscopyCornea03 medical and health sciences0302 clinical medicineOct angiographyCorneal OpacityOphthalmologyMedicineHumansIn patientCorneal NeovascularizationProspective StudiesFluorescein AngiographyAgedAged 80 and overSlit lampbusiness.industryEpithelium CornealReproducibility of ResultsGeneral MedicineOptical coherence tomography angiographyMiddle Agedmedicine.diseaseeye diseasesPeripheralOphthalmologyCorneal neovascularization030221 ophthalmology & optometryCorneal vascularizationFemalesense organsbusiness030217 neurology & neurosurgeryTomography Optical CoherenceFollow-Up Studies

description

Purpose The major goal of this study was to test the hypothesis that in patients with peripheral hypertrophic subepithelial corneal opacification (PHSCO), visualization of corneal vessels is better with optical coherence tomography angiography (OCTA) than with conventional slit lamp microphotography. Methods Patients with PHSCO were included in this prospective study. The corneal findings were photographed using a slit lamp camera (Haag Streit BM 900® ) and visualized with anterior-segment OCT (Optovue XR Avanti, Fremont, California, USA). Additionally, OCTA with the Angiovue Imaging™ System was performed in the area of PHSCO. Results Thirty-four eyes of 19 patients (26% male and 74% female) with PHSCO were included in this study. In 21 eyes, vascularization in the area of PHSCO was visualized with the Angiovue-OCT, whereas only 10 eyes presented vessels in slit lamp photographs. Conclusion Optical coherence tomography angiography allows better visualization of corneal neovascularization than slit lamp photography in patients with PHSCO. Corneal opacifications were found predominantly nasally, which was reflected by a local enlargement of corneal thickness.

yearjournalcountryeditionlanguage
2018-04-19Acta ophthalmologica
10.1111/aos.13800https://pubmed.ncbi.nlm.nih.gov/29671946