6533b839fe1ef96bd12a665f

RESEARCH PRODUCT

Sensitive and selective plasmonic assay for spermine as biomarker in human urine.

Julia Pérez-prietoN. Jornet-martínezPilar Campíns-falcóYolanda Moliner-martínezMaría González-béjar

subject

AnalyteChromatographyChemistrySpermineMetal NanoparticlesUrineUrinalysisHighly selective3. Good healthAnalytical Chemistrychemistry.chemical_compoundBiomarkerBiochemistryColloidal goldLimit of DetectionHumansAmine gas treatingColorimetrySpermineGoldBiomarkers

description

A simple, fast, and highly selective and sensitive colorimetric assay to detect nanomolar levels of spermine in human urine (healthy donors, cancer patients) is reported. This assay is based on the absence of a competitive organic capping on the gold nanoparticles together with the high affinity of the amine groups of the analyte for the nanoparticle surface.

yearjournalcountryeditionlanguage
2014-01-21Analytical chemistry
10.1021/ac404165jhttps://pubmed.ncbi.nlm.nih.gov/24428122