6533b839fe1ef96bd12a6d1b

RESEARCH PRODUCT

Bisphosphonates in the era of antiangiogenic targeted therapy

Frederik C. Roos

subject

Oncologymedicine.medical_specialtybusiness.industryUrologymedicine.medical_treatmentmedicine.diseaseTargeted therapyRenal cell carcinomaInternal medicinemedicineIn patientmedicine.symptomBone painbusinessKidney cancer

description

Bone is the second most common metastatic site in patients presenting with metastatic renal cell carcinoma. Bisphosphonates have been approved to reduce bone pain and the risk of skeletal-related events (SREs) in such patients; however, new research suggests bisphosphonates do not improve survival or prevent development of SREs.

https://doi.org/10.1038/nrurol.2014.120