6533b839fe1ef96bd12a6dd9

RESEARCH PRODUCT

Antimicrobial activity of essential oil ofArtemisia judaicaL. from Algeria against multi-drug resistant bacteria from clinical origin

N. BenmansourMaría Amparo BlázquezA. BenmansourM. C. González-masF. El HanbaliA. El HakmaouiM. Akssira

subject

Minimum bactericidal concentration010405 organic chemistryMulti drug resistant bacteriaChemistryGeneral ChemistryAntimicrobial01 natural sciences0104 chemical scienceslaw.inventionMicrobiologyArtemisia judaicaMultiple drug resistance010404 medicinal & biomolecular chemistryMinimum inhibitory concentrationlawBotanyAntibacterial activityEssential oilFood Science

description

Artemisia judaica L. essential oil was studied for antibacterial activity against various clinical isolates of bacteria resistant to a number of antibiotics. The antibacterial activity was evaluated against 20 multidrug resistant (MDR) of clinical origin compared to standard ATCC strains. The strains that showed resistance against the maximum number of antibiotics tested were selected for an antibacterial assay by three methods: Disc diffusion method, microatmosphere and dilution method. The obtained results demonstrated that the A. judaica essential oil possessed an excellent inhibitory effect against all of the tested strains. The most potent results were obtained against MRSA (Methicillin Resistant Staphylococcus aureus), Staphylococcus aureus and Bacillus subtilis (their MIC was 8.75 µg/ml). MIC (Minimal Inhibitory Concentration) and MBC (Minimal Bactericidal Concentration) values for essential oil against all tested strains were equal. According to GC-MS analysis forty-one constituents were identified, which represented 84.66 % of the total essential oil, being piperitone (73.4 %) the main compound. Copyright © 2015 John Wiley & Sons, Ltd.

yearjournalcountryeditionlanguage
2015-10-26Flavour and Fragrance Journal
https://doi.org/10.1002/ffj.3291