0000000000055119

AUTHOR

María Amparo Blázquez

showing 38 related works from this author

Untargeted metabolomics of rind essential oils allowed to differentiate two closely related clementine varieties

2021

[EN] Chemical characterization of clementine varieties (Citrus clementina Hort. ex Tan.) essential oils (EO) can lead to variety identification and valorization of their potential use in food and aroma industries. The goal of this study was the chemometric discrimination between two very closely related and morphologically identical clementine varieties, Clemenules (NL) and Clemenpons (PO), based on their rind EO, to identify the differential volatile organic compounds (VOCs) and to determine their antioxidant capacity. EO rind volatile profile was determined by gas chromatography coupled to mass spectrometry in Citrus fruit at different ripening stages grown two independent years in two di…

antioxidant activity<i>Citrus clementina</i>Plant ScienceflavedoSesquiterpeneArticlechemistry.chemical_compoundvolatile organic compoundsBIOQUIMICA Y BIOLOGIA MOLECULARCitrus clementinaFood scienceEcology Evolution Behavior and SystematicsAromaEcologybiologyBotanyClemenulesFood preservationVolatile organics compoundsRipeningClemenponsDodecanalQ01 Food science and technologybiology.organism_classificationF60 Plant physiology and biochemistryUntargeted metabolomicschemistryU30 Research methodsQK1-989clemenulesGas chromatographycitrus clementinaclemenponsClementineF30 Plant genetics and breeding
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Bioactivity of essential oils in phytopathogenic and post-harvest fungi control

2017

[EN] Commercial thyme and lavender essential oils were analysed by GC/MS. Sixty-six compounds accounting for 98.6¿99.6% of total essential oil were identified. Thymol (52.14 ± 0.21%), followed by pcymene (32.24 ± 0.16%), carvacrol (3.71 ± 0.01%) and ¿-terpinene (3.34 ± 0.02%), were the main compounds in thyme essential oil, while large amounts of oxygenated monoterpenes linalool acetate (37.07 ± 0.24%) and linalool (30.16 ± 0.06%) were found in lavender one. In vitro antifungal activity of the essential oils was evaluated at 200 and 300 ¿g/mL against 10 phytopathogenic and post-harvest fungi, which significantly affect agriculture. Micelial growth inhibition was calculated for each tested f…

AntifungalLavendermedicine.drug_classAcyclic MonoterpenesBOTANICAPlant ScienceFungusCyclohexane MonoterpenesMicrobial Sensitivity Tests01 natural sciencesBiochemistryGas Chromatography-Mass SpectrometryAnalytical Chemistrylaw.inventionThymus Plantchemistry.chemical_compoundLinaloollawLavenderBotanymedicineOils VolatilePlant OilsCarvacrolFood scienceAntifungal activityThymolEssential oilBIOLOGIA VEGETALbiology010405 organic chemistryOrganic ChemistryFungiThymebiology.organism_classificationThymol0104 chemical sciencesFungicides Industrial010404 medicinal & biomolecular chemistryLavandulachemistryEssential oilsMonoterpenesCymenesGrowth inhibition
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Elsholtzia blandaBenth: New Citral-rich Chemotypes from India

2012

The essential oils of the previously un-investigated aerial parts of Elsholtzia blanda were analyzed by GC and GC/MS. The yields of the oil were found to be 0.93 and 1.70% on fresh weight basis. A total of 25 compounds, representing 82.8% and 87.9% of the oil, were identified. The main compounds were geranial (43.5%–48.8%), neral (31.7%–34.7%), E-isocitral (1.2%–0.1%), and caryophyllene oxide (1.6%–0.7%). These two cultivars have the potential to compete with commercial citral oils.

PharmacologyElsholtzia blandabiologyChemotypeChemistryFresh weightbiology.organism_classificationCitrallaw.inventionHorticulturechemistry.chemical_compoundComplementary and alternative medicineCaryophyllene oxidelawBotanyLamiaceaeCultivarEssential oilJournal of Herbs, Spices &amp; Medicinal Plants
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Chromone and phenanthrene alkaloids from Dennettia tripetala.

2002

Dennettine, a new 2,6-dimethoxychromone and three known phenanthrene alkaloids (uvariopsine, stephenanthrine and argentinine) in addition to the phenolic and known compound vanillin were isolated from the roots of Dennettia tripetala. Their structures were determined by physical and spectroscopical one dimensional (1D) and 2D-NMR analysis, including heteronuclear multiple bond correlation and nuclear Overhauser enhancement spectroscopy.

Magnetic Resonance SpectroscopyTertiary amineStereochemistryAnnonaceaePharmacognosyPlant RootsStephenanthrinechemistry.chemical_compoundAlkaloidsDrug DiscoveryOrganic chemistrySpectroscopyDennettia tripetalabiologyMolecular StructureVanillinUvariopsineGeneral ChemistryGeneral MedicineNuclear magnetic resonance spectroscopyPhenanthrenePhenanthrenesbiology.organism_classificationchemistryHeteronuclear moleculeAnnonaceaeChromonesChromoneChemicalpharmaceutical bulletin
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Reactive oxygen species (ROS) generation inhibited by aporphine and phenanthrene alkaloids semi-synthesized from natural boldine.

2004

Four phenanthrene and one aporphine alkaloids semi-synthesized from boldine were evaluated for their inhibitory effect on reactive oxygen species (ROS) generation. ROS generation by neutrophils stimulated with N-formyl-methionyl-leucyl-phenylalanine was inhibited in a concentration dependent manner. Alkaloids exerted similar inhibitory effect in the hypoxanthine-xanthine oxidase system than in stimulated neutrophils, which could be attributed to a direct ROS scavenging activity. None of the alkaloids assayed had any effect on xanthine oxidase activity. Therefore the synthesized alkaloids might constitute an alternative therapy in inflammation disorders in which ROS generation is involved.

AporphinesStereochemistryNeutrophilsInflammationcomplex mixtureschemistry.chemical_compoundRos scavengingAlkaloidsDrug DiscoverymedicineBoldineHumansheterocyclic compoundsAporphineInhibitory effectchemistry.chemical_classificationReactive oxygen speciesOxidase testDose-Response Relationship DrugChemistryorganic chemicalsGeneral ChemistryGeneral MedicinePhenanthrenePhenanthrenesBiochemistrymedicine.symptomReactive Oxygen SpeciesChemicalpharmaceutical bulletin
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Composition and Antimicrobial Activity of Essential Oil ofAnthemis tenuisectaBall

2007

Abstract The Chemical composition of the essential oil of Anthemis tenuisecta Ball. (Anthemideae) was analyzed by gas Chromatography-mass spectrometry (GC-MS). Forty eight components accounting for 89.5 % of the oil were identified, being camphor (17.5 %), 6-methyl-5-hepten-2-one (17.1 %), borneol (11.5 %), sesquicineole (11%) and camphene (5.7 %) the main compounds. In the antibacterial diffusion assay, the oil showed activity against Gram-positive bacteria.

biologyOrganic ChemistryAntimicrobialbiology.organism_classificationBiochemistryAnalytical Chemistrylaw.inventionBorneolchemistry.chemical_compoundCamphorchemistrylawAnthemideaeCampheneOrganic chemistryFood scienceAntibacterial activityChemical compositionEssential oilJournal of Essential Oil Bearing Plants
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Chemical Composition of the Essential Oil of Zingiber Zerumbet Var. Darcyi

2012

The chemical composition of essential oil obtained by hydrodistillation method from the rhizomes of Z. zerumbet var. darcyi was determined by GC and GC-MS. Thirty-three compounds, accounting for 93.6% of the oil were identified including twenty compounds in minor (0.1-0.6%) and eight in trace (&lt;0.05%) amounts. The main compounds were zerumbone (69.9%) α-humulene (12.9%), humulene epoxide II (2.5%), caryophyllene oxide (1.1%) and camphene (1.9%). In this analysis, it has been found that the variety could be used as an additional new source of natural zerumbone besides Zingiber zerumbet. This is a first report on the analysis of Z. zerumbet var. darcyi oil.

PharmacologybiologyHumuleneTraditional medicinePlant ScienceGeneral Medicinebiology.organism_classificationlaw.inventionRhizomechemistry.chemical_compoundComplementary and alternative medicinechemistryZingiber zerumbetlawDrug DiscoveryBotanyCampheneZingiberaceaeGas chromatography–mass spectrometryChemical compositionEssential oilNatural Product Communications
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Curcuma longa L. Rhizome Essential Oil from Extraction to Its Agri-Food Applications. A Review

2021

Curcuma longa L. rhizome essential oil is a valuable product in pharmaceutical industry due to its wide beneficial health effects. Novel applications in the agri-food industry where more sustainable extraction processes are required currently and safer substances are claimed for the consumer are being investigated. This review provides information regarding the conventional and recent extraction methods of C. longa rhizome oil, their characteristics and suitability to be applied at the industrial scale. In addition, variations in the chemical composition of C. longa rhizome and leaf essential oils regarding intrinsic and extrinsic factors and extraction methods are also analysed in order to…

0106 biological sciencesPreservativeantioxidantOrganolepticPlant ScienceReview01 natural sciencesessential oillaw.invention<i>Curcuma longa</i>0404 agricultural biotechnologyextraction methodslawchemical compositionCurcumaherbicidalEcology Evolution Behavior and SystematicsEssential oilCurcuma longaEcologybiologybusiness.industryExtraction (chemistry)Botany04 agricultural and veterinary sciencesbiology.organism_classification040401 food scienceBiotechnologyRhizomeAgricultureQK1-989Environmental scienceantimicrobialExtraction methodsagri-food industrybusiness010606 plant biology & botanyPlants
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Phytotoxic Effects of Commercial Eucalyptus citriodora, Lavandula angustifolia, and Pinus sylvestris Essential Oils on Weeds, Crops, and Invasive Spe…

2019

Background: essential oils are well known for their pharmacological effectiveness as well as their repellent, insecticide, and herbicide activities. The emergence of resistant weeds, due to the overuse of synthetic herbicides, makes it necessary to find natural alternatives for weed control. The aim of this study was to evaluate the phytotoxic effects of Eucalyptus citriodora, Lavandula angustifolia, and Pinus sylvestris, three common commercial essential oils, on weeds (Portulaca oleracea, Lolium multiflorum, and Echinochloa crus-galli), food crops (tomato and cucumber), and the invasive species Nicotiana glauca. Methods: to determine herbicidal effects, essential oils were tested at diffe…

0106 biological sciencesE. citriodoraPlant WeedsPharmaceutical Sciencephytotoxicity<i>E. citriodora</i>01 natural sciencesAnalytical Chemistrylaw.inventionlawDrug DiscoveryRadicleGC–MSLavandula angustifoliaEucalyptusbiologyfood and beveragesPinus sylvestris<i>L. angustifolia</i>HorticultureLavandulaChemistry (miscellaneous)GerminationEucalyptus citriodoraMolecular MedicineCrops AgriculturalWeed ControlGerminationL. angustifoliaArticleGas Chromatography-Mass Spectrometrylcsh:QD241-441lcsh:Organic chemistryP. sylvestrisOils VolatilePhysical and Theoretical Chemistryessential oilsEssential oil<i>P. sylvestris</i>HerbicidesfungiOrganic ChemistryLolium multiflorumbiology.organism_classification0104 chemical sciences010404 medicinal & biomolecular chemistrySeedlingsSeedlingIntroduced SpeciesWeed010606 plant biology & botanyMolecules
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Inhibition of bacterial virulence factors of foodborne pathogens by paprika (Capsicum annuum L.) extracts

2022

Abstract Capsicum annuum extracts of different polarities were tested for their antimicrobial, antibiofilm, and anti-Quorum sensing (QS) activity against several pathogenic microorganisms and possible toxic effects using an in vivo model (Galleria mellonella L.). Hexane (HE) and Chloroform extract (CE) were the most active in inhibiting biofilm formation of the eight bacteria tested, with inhibition percentages between 22 and 88% for a concentration of 100 μg/mL. These extracts were potent inhibitors of Staphylococcus aureus biofilm, and microscopy analysis confirmed a significant reduction in adhered cells. Moreover, polystyrene surfaces coated with these extracts decreased Staph. aureus a…

biologyChemistryPseudomonas aeruginosaBiofilmSwarming motilitybiochemical phenomena metabolism and nutritionmedicine.disease_causebiology.organism_classificationAntimicrobialMicrobiologychemistry.chemical_compoundPyocyaninStaphylococcus aureusmedicineCoagulaseBacteriaFood ScienceBiotechnologyFood Control
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Antibiofilm activity of coriander (Coriander sativum L.) grown in Argentina against food contaminants and human pathogenic bacteria

2020

Abstract Bacterial spoilage of food and other infections are a coordinated mechanism controlled by quorum sensing (QS), which regulate the expression of virulence factors, such as biofilm. The antimicrobial, antibiofilm, anti-QS and anti-swarming properties of hexane (HE), chloroform (CE), ethyl acetate (EAE), methanolic (ME) and total methanolic (TME) extracts of coriander grown in Argentina were investigated. In vivo extracts toxicity using Galleria mellonella L. model and chemical composition (GC-MS) were also assessed. The antibiofilm activity of polystyrene surfaces coated with the most active extracts was evaluated. At non-inhibitory growth concentrations, extracts showed a strong ant…

0106 biological sciencesbiology010405 organic chemistryPseudomonas aeruginosaChemistryFood spoilageBiofilmPathogenic bacteriabiochemical phenomena metabolism and nutritionbiology.organism_classificationmedicine.disease_causeAntimicrobial01 natural sciences0104 chemical sciencesSalmonella entericaStaphylococcus aureusmedicineFood scienceAgronomy and Crop ScienceBacteria010606 plant biology & botanyIndustrial Crops and Products
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New alkaloid antibiotics that target the DNA topoisomerase I of Streptococcus pneumoniae

2011

16 pags, 3 figs, 3 tabs

Models MolecularTopoisomerase-I Inhibitormedicine.disease_causeMicrobiologyBiochemistryCell LineMicrobiology03 medical and health scienceschemistry.chemical_compoundAlkaloidsBacterial ProteinsStreptococcus pneumoniaemedicineHumansAporphineMolecular BiologyEscherichia coli030304 developmental biologychemistry.chemical_classification0303 health sciencesDose-Response Relationship Drugbiology030306 microbiologyTopoisomeraseCell BiologyPhenanthrenesProtein Structure TertiaryAnti-Bacterial Agents3. Good healthStreptococcus pneumoniaeEnzymeDNA Topoisomerases Type IchemistryBiochemistrybiology.proteinDNA supercoilTopoisomerase I InhibitorsGrowth inhibitionJournal of Biological Chemistry 286: 6402-6413 (2011)
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Laurel extracts inhibit quorum sensing, virulence factors and biofilm of foodborne pathogens

2020

Antimicrobial, antibiofilm, anti-Quorum sensing (QS) and virulence factors inhibitory capacity of different polarity Laurus nobilis extracts against several pathogenic microorganisms were studied. Some extracts exhibited antibiotic effect against Staphylococcus aureus multidrug-resistant strains. However, all extracts (100 µg/mL) inhibited to some extent the biofilm of most bacteria tested (until 40% for Gram-negative and 76% for Gram-positive). Hexane (HE) and chloroform extract (CE) were potent inhibitors of S. aureus biofilm and the microscopies further confirmed an important reduction in adherent cells. Polystyrene surfaces coated with these extracts showed a decrease in bacterial adhes…

0106 biological sciencesPYOCYANINVirulenceSwarming motilitymedicine.disease_cause01 natural sciencesMicrobiology//purl.org/becyt/ford/1 [https]chemistry.chemical_compound0404 agricultural biotechnologyPyocyanin010608 biotechnologymedicine//purl.org/becyt/ford/1.6 [https]biologyENZYME INHIBITIONPseudomonas aeruginosaChemistryBiofilm04 agricultural and veterinary sciencesbiology.organism_classification040401 food scienceSWARMINGQuorum sensingStaphylococcus aureusBIOFILMBacteriaFATTY ACIDSFood Science
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Lemon Oils Attenuate the Pathogenicity of Pseudomonas aeruginosa by Quorum Sensing Inhibition

2021

The chemical composition of three Citrus limon oils: lemon essential oil (LEO), lemon terpenes (LT) and lemon essence (LE), and their influence in the virulence factors production and motility (swarming and swimming) of two Pseudomonas aeruginosa strains (ATCC 27853 and a multidrug-resistant HT5) were investigated. The main compound, limonene, was also tested in biological assays. Eighty-four compounds, accounting for a relative peak area of 99.23%, 98.58% and 99.64%, were identified by GC/MS. Limonene (59–60%), γ-terpinene (10–11%) and β-pinene (7–15%) were the main compounds. All lemon oils inhibited specific biofilm production and bacterial metabolic activities into biofilm in a dose-dep…

CitrusCITRUS PEELPharmaceutical ScienceSwarming motilitypyocyaninmedicine.disease_causebiofilmAnalytical Chemistrylaw.invention//purl.org/becyt/ford/1 [https]Terpenechemistry.chemical_compoundQD241-441lawDrug Resistance Multiple BacterialQUORUM SENSINGDrug DiscoveryCitrus peelFood scienceBicyclic Monoterpenes0303 health sciencesPancreatic ElastaseVirulencequorum sensing04 agricultural and veterinary sciences040401 food scienceAnti-Bacterial AgentsmotilityChemistry (miscellaneous)Pseudomonas aeruginosaMolecular MedicineBIOFILMVIRULENCE FACTORSSignal TransductionPYOCYANINVirulence FactorsCyclohexane Monoterpenes<i>Citrus</i> peelArticleGas Chromatography-Mass Spectrometry03 medical and health sciences0404 agricultural biotechnologyPyocyaninBacterial ProteinsMOTILITYOils VolatilemedicinePlant OilselastasePhysical and Theoretical Chemistry//purl.org/becyt/ford/1.6 [https]Essential oilVolatile Organic CompoundsLimonene030306 microbiologyPseudomonas aeruginosaOrganic ChemistryBiofilmQuorum sensingchemistryBiofilmsPyocyanineLimoneneELASTASEMolecules
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Chemical Composition of the Essential Oils ofPistacia atlanticaDesf.

2005

The chemical composition of the three essential oils obtained by hydrodistillation of the resin, leaves and fruits of Pistacia atlantica Desf. (Anacardiaceae) was studied by GC and GC/MS. Monoterpene hydrocarbons constituted the main chemical group in the resin oil, with α-pinene (42.9%) and β-pinene (13.2%) as the major components. Oil of the fruits contained high amounts of oxygenated monoterpenes, with bornyl acetate (21.5%) as the major component, while oxygenated monoterpenes and sesquiterpenes were found to predominate in the oil of leaves among which terpinen-4-ol (21.7%) and elemol (20.0%) were the most abundant components.

chemistry.chemical_compoundbiologyChemistryMonoterpeneBotanyBornyl acetateTerpinen-4-olAnacardiaceaePistacia atlanticaGeneral Chemistrybiology.organism_classificationChemical compositionJournal of Essential Oil Research
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Encapsulated Limonene: A Pleasant Lemon-Like Aroma with Promising Application in the Agri-Food Industry. A Review

2020

International audience; Limonene, mainly found as a major component in Citrus spp., has been proven to possess a valuable potential as sustainable replacement to synthetic pesticides and food preservatives. This review intends to give a clear overview of the principal emerging applications of limonene in the agri-food industry as antimicrobial, herbicidal and antioxidant agent. To successfully use limonene in a greener agri-food industry, its preservation had become a top concern for manufacturers. In order to elucidate the most efficient and sustainable manner to encapsulate limonene, the different techniques and materials tested up to the present are also reviewed. In general, encapsulati…

antioxidantFood industryPharmaceutical ScienceReview02 engineering and technologyAntioxidantsAnalytical ChemistryFoodborne Diseaseslcsh:QD241-441chemistry.chemical_compound0404 agricultural biotechnologyAnti-Infective Agentslcsh:Organic chemistrySustainable systemsDrug Discovery[CHIM]Chemical SciencesHumansPhysical and Theoretical ChemistryherbicidalAroma2. Zero hungerFood PreservativesLimonenebiologybusiness.industryOrganic Chemistry04 agricultural and veterinary sciences15. Life on land021001 nanoscience & nanotechnologybiology.organism_classification040401 food scienceMicrosphereschemistryChemistry (miscellaneous)Food productsFood PreservativesMolecular Medicinelimoneneantimicrobialencapsulationagri-food industryBiochemical engineering0210 nano-technologybusinessMolecules
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Chemical composition, herbicidal and antifungal activity of Satureja cuneifolia essential oils from Spain

2016

The chemical composition of essential oils from Satureja cuneifolia growing in east Spain was analyzed by GC, GC/MS. Forty-five compounds accounting for 99.1% of the total oil were identified. Camphor (47.6%), followed by camphene (13.6%) were the main compounds. Their herbicidal and antifungal activity was tested in vitro against three weeds (Amaranthus hybridus, Portulaca oleracea and Conyza canadensis) and eleven common pathogenic or saprophytic fungi (Phytophthora citrophthora, P. palmivora, Pythium litorale, Verticillium dahlia, Rhizoctonia solani, Penicillium hirsutum, Colletotrichum gloeosporioides, Phaeoacremonium aleophilum, Phaemoniella chlamydospora, Cylindrocarpon liriodendri a…

0106 biological sciencesHerbicidal activityAntifungal AgentsPhytophthora citrophthoraAmaranthus hybridusBOTANICAPlant WeedsGerminationPlant Science01 natural sciencesEssential oillaw.inventionRhizoctonia solanichemistry.chemical_compoundlawDrug DiscoveryOils VolatileAntifungal activityEssential oilSatureja cuneifoliaPharmacologyCylindrocarponBIOLOGIA VEGETALbiologyHerbicidesPlant ExtractsSaturejaFungiGeneral MedicineVerticilliumbiology.organism_classification0104 chemical sciencesPhaeoacremonium aleophilum010404 medicinal & biomolecular chemistryHorticultureComplementary and alternative medicinechemistrySpainCamphene010606 plant biology & botany
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Composition and Antibacterial Activity of Essential Oils ofCladanthus arabicusCass. (Asteraceae)

2005

Abstract The chemical composition of the essential oils of the aerial parts (stems and leaves: sample A) and flowers (sample B) of Cladanthus arabicus Cass., were analysed by GC-MS. Monoterpenes hydrocarbons constituted the main chemical group in both essential oils, with Sabinene, β-pinene, α-pinene, myrcene, α-phellandrene and p-cymene as the main compounds. Sample A was tested for its antimicrobial activity against six Gram positive and negative bacteria. Results showed that the oil exhibited a significant antibacterial activity.

biologyOrganic ChemistrySabineneAsteraceaebiology.organism_classificationAntimicrobialBiochemistryAnalytical Chemistrylaw.inventionchemistry.chemical_compoundchemistrylawMyrceneBotanyComposition (visual arts)Antibacterial activityChemical compositionEssential oilJournal of Essential Oil Bearing Plants
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Ginger and Turmeric Essential Oils for Weed Control and Food Crop Protection

2019

Ginger and turmeric are two food ingredients that are in high demand due to their flavor and positive effects on health. The biological properties of these spices are closely related to the aromatic compounds they contain. The chemical compositions of their essential oils and their in vitro phytotoxic activity against weeds (Portulaca oleracea, Lolium multiflorum, Echinochloa crus-galli, Cortaderia selloana, and Nicotiana glauca) and food crops (tomato, cucumber, and rice) were studied. Forty-one compounds, accounting for a relative peak area of 87.7% and 94.6% of turmeric and ginger essential oils, respectively, were identified by Gas Chromatography&ndash

weed controlgingerPlant Sciencephytotoxicity01 natural sciencesArticlelaw.inventionHypocotyl0404 agricultural biotechnologylawRadiclegas chromatography–mass spectrometryessential oilsEcology Evolution Behavior and SystematicsEssential oilEcologybiology010401 analytical chemistryfungiturmericBotanyfood and beverages04 agricultural and veterinary sciencesLolium multiflorumfood cropsbiology.organism_classification040401 food science0104 chemical sciencesHorticultureSeedlingGerminationQK1-989PhytotoxicityBioherbicidePlants
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Chemical composition and antimicrobial activity of the essential oil ofCurcuma leucorhizaRoxb

2012

The essential oils obtained by hydrodistillation from the rhizomes and leaves of Curcuma leucorhiza Roxb. were analyzed by gas chromatography (GC) and GC/mass spectrometry (GC/MS) for the first time. A total of forty-nine compounds were identified in both oils. The main compounds in the rhizome and leaf oils were germacrone (9.6–19.7%), curdione (19.1–19.5%), camphor (7.2–8.1%), 1,8-cineole (4.0–7.4%), curzerene (3.0–5.7%), linalool (5.2–5.4%), neo-curdione (2.8–4.6%) and isoborneol (2.0–3.8%). Screening of the essential oils showed promising antibacterial activity (7–16 mm inhibition zone) against Streptococcus mutans, Pseudomonas putida, Bacillus subtilis, Klebsiella pneumoniae and antifu…

biologyAspergillus nigerAspergillus flavusCurzereneGermacroneGeneral Chemistrybiology.organism_classificationMicrobiologyAspergillus fumigatuslaw.inventionCamphorchemistry.chemical_compoundchemistrylawFood scienceCurcumaEssential oilJournal of Essential Oil Research
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Compositions of the Volatile Oils of Citrus Macroptera and C. Maxima

2012

The essential oils obtained by hydrodistillation from the fresh peels of Citrus macroptera Montr. and C maxima(Burm.) Merr. were analyzed by GC and GC/MS. The yields of oil ranged from 0.53% in C macroptera to 0.13% in C maxima cultivar (white). Forty-seven compounds were identified in the oils with limonene (55.3-80.0%), dodecyl acrylate (2.2-8.0%), geranial (0.4-3.5%), trans-linalool oxide (1.0-2.8%), α-terpineol (0.7-2.3%), linalool (0.7-1.5%) and cis- linalool oxide (0.5-1.4%) identified as major compounds. The oil of C. macroptera contained limonene (55.3%), β-caryophyllene (4.7%) and geranial (3.5%) as main compounds. Similarly, oils from two C maxima(pink and white) cultivars were r…

PharmacologyLimonenebiologyChemistryfood and beveragesPlant ScienceGeneral Medicinebiology.organism_classificationlaw.inventionchemistry.chemical_compoundRutaceaeComplementary and alternative medicineLinaloollawDrug DiscoveryNootkatoneCultivarFood scienceGas chromatography–mass spectrometryMaximaEssential oilNatural Product Communications
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Chemotaxonomic value of the essential oil compounds in species of Teucrium pumilum aggregate

2000

Volatile compounds from the aerial parts of Teucrium lepicephalum Pau and Teucrium carolipaui C. Vicioso ex Pau, both belonging to the Teucrium pumilum aggregate, were analysed by capillary GC and GC-MS. From the common and specific compounds (mono- and sesquiterpenes) of the two taxa, chemical characterization was carried out and taxonomic relationships were assessed. Application of the cluster and k-means discriminant analysis shows a differential chemical relationship between T. lepicephalum and Teucrium carolipaui.

Chromatography GasLamiaceaebiologyMonoterpenePlant ScienceGeneral MedicineHorticulturebiology.organism_classificationSesquiterpeneBiochemistrylaw.inventionTeucriumTerpenechemistry.chemical_compoundSpecies SpecificitychemistryChemotaxonomylawBotanyOils VolatileLamiaceaeTaxonomy (biology)VolatilizationMolecular BiologyEssential oilPhytochemistry
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Antimicrobial activity of essential oil ofArtemisia judaicaL. from Algeria against multi-drug resistant bacteria from clinical origin

2015

Artemisia judaica L. essential oil was studied for antibacterial activity against various clinical isolates of bacteria resistant to a number of antibiotics. The antibacterial activity was evaluated against 20 multidrug resistant (MDR) of clinical origin compared to standard ATCC strains. The strains that showed resistance against the maximum number of antibiotics tested were selected for an antibacterial assay by three methods: Disc diffusion method, microatmosphere and dilution method. The obtained results demonstrated that the A. judaica essential oil possessed an excellent inhibitory effect against all of the tested strains. The most potent results were obtained against MRSA (Methicilli…

Minimum bactericidal concentration010405 organic chemistryMulti drug resistant bacteriaChemistryGeneral ChemistryAntimicrobial01 natural sciences0104 chemical scienceslaw.inventionMicrobiologyArtemisia judaicaMultiple drug resistance010404 medicinal & biomolecular chemistryMinimum inhibitory concentrationlawBotanyAntibacterial activityEssential oilFood ScienceFlavour and Fragrance Journal
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Effect of boldine, secoboldine, and boldine methine on angiotensin II-induced neutrophil recruitment in vivo.

2005

AbstractAngiotensin-II (Ang-II) has inflammatory activity and is involved in different diseases associated with the cardiovascular system. This study has evaluated the effect of boldine (B), and two phenanthrene alkaloids semisynthesized by us, secoboldine (SB) and boldine methine (BM), on Ang-II-induced neutrophil recruitment. Intraperitoneal administration of 1 nM Ang-II induced significant neutrophil accumulation, which was maximal at 4–8 h. BM inhibited neutrophil infiltration into the peritoneal cavity at 4 h and 8 h by 73% and 77%, respectively, SB at 8 h by 55%, and B had no effect on this response. Although BM inhibited the release of cytokine-inducible neutrophil chemoattractant/ke…

KeratinocytesMaleChemokineAporphinesEndotheliumNeutrophilsImmunologyChemokine CXCL2InflammationPharmacologyRats Sprague-Dawleychemistry.chemical_compoundIn vivomedicineImmunology and AllergyBoldineAnimalsHumansInfusions ParenteralPlatelet Activating FactorReceptorchemistry.chemical_classificationReactive oxygen speciesbiologyMolecular StructureAngiotensin IIMonokinesInterleukin-8Endothelial CellsCell BiologyPhenanthrenesAngiotensin IIRatsP-Selectinmedicine.anatomical_structureBiochemistrychemistrybiology.proteinIntercellular Signaling Peptides and Proteinsmedicine.symptomChemokinesReactive Oxygen SpeciesChemokines CXCJournal of leukocyte biology
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Further Flavonoids and Other Phenolics of Thymus webbianus Rouy

1994

Abstract Seven different flavonoids from the aerial parts of Thymus webbianus were isolated. They were identified by UV spectra, TLC and HPLC-DAD as luteolin, api­genin, eryodictiol, naringenin, luteolin-7-O-glucoside, apigenin-7-O-glucoside and apigenin-6,8-di-C-glucoside. Other phenolics characterized by HPLC-DAD analysis were: protocatechuic, chlorogenic, syringic, p-coumaric and 3,5-dicaffeoylquinic acids.

ChromatographybiologyChemistryLamiaceaebiology.organism_classificationHigh-performance liquid chromatographyGeneral Biochemistry Genetics and Molecular BiologyZeitschrift für Naturforschung C
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Influence of the Storage of Cistus ladanifer L. Bales from Mechanised Harvesting on the Essential Oil Yield and Qualitative Composition

2021

Cistus ladanifer is a Mediterranean native plant from which valuable products, such as essential oil, are obtained. Manual harvesting of the plants in wild shrublands is usual during short periods of time. Their mechanised harvesting could increase the volume of harvested plants and prevent fires, further storage of the plants collected being necessary. The objective of this work is to study the influence of the storage period of mechanically harvested bales on the essential oil yield and qualitative composition. The harvesting trials were carried out with an adapted commercial harvester baler and the storage of the bales was performed indoors during 1–7 days, 15–30 days and 100–120 days. A…

0106 biological sciencesChromatography Gasdistillation020209 energyPharmaceutical ScienceBiomassOrganic chemistry02 engineering and technology01 natural sciencesCistus ladaniferGas Chromatography-Mass SpectrometryArticleessential oilAnalytical Chemistrylaw.inventionSteam distillationmechanised harvestingQD241-441<i>Cistus ladanifer</i> L.lawDrug Discovery0202 electrical engineering electronic engineering information engineeringOils VolatilePhysical and Theoretical ChemistryDistillationEssential oilbiologySuperheated steamCistusbiology.organism_classificationrockroseHorticulturePilot plantChemistry (miscellaneous)pilot plantMonoterpenesMolecular MedicineEnvironmental scienceComposition (visual arts)Cistus ladanifer L.010606 plant biology & botanyMolecules
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Comparative GC-MS Analysis of Bay Leaf (Laurus nobilisL.) Essential Oils in Commercial Samples

2015

Chemical composition of Laurus nobilis essential oils traded as spice and medicinal items was analyzed by gas chromatography-mass spectrometry. Sixty-four compounds accounting between 91–99% of the total oil was identified. Qualitative and quantitative differences were found among essential oils obtained from bay leaves used both for cooking and medicinal purposes. The oxygenated compounds were the principal fraction in all analyzed oils and consisted in oxygenated monoterpenes (73.13%), in medicinal essential oil and oxygenated monoterpenes (37.60 and 29.82%), oxygenated sesquiterpenes (15.98 and 22.99%), and phenylpropanoids (24.78 and 26.33%), respectively, in commercial food items. A hi…

LauraceaeBiologybiology.organism_classificationTerpenoidfood.foodlaw.inventionEugenolchemistry.chemical_compoundLaurus nobilisfoodchemistryMethyl eugenollawBotanyFood scienceGas chromatography–mass spectrometryChemical compositionEssential oilFood ScienceInternational Journal of Food Properties
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In vitro antibacterial and biofilm inhibitory activity of the sawdust essential oil of Tetraclinis articulata (vahl) against catheter-associated Stap…

2021

Abstract The aim of the present study was to determine the chemical composition, antibacterial and antibiofilm activities of the essential oil of sawdust from root burl wood of T. articulata. Nine strains including 8 clinical isolates from catheters-related infections and one ATCC 25923 were tested. Twenty-seven different compounds were identified by GC–MS in the essential oil of T. articulata extracted by hydrodistillation. Carvacrol and cedrol were the principal compounds representing 34.37 ± 0.07 and 11.07 ± 0.09 respectively. The EO had a strong antibacterial activity against all strains including one Multidrug-Resistant (MDR) and two Methicillin-Resistant S. aureus strains. Inhibition …

Staphylococcus aureusmedicine.disease_causeEssential oillaw.inventionCedrolboatschemistry.chemical_compoundboats.ship_classlawArticulatamedicineCarvacrolFood scienceEssential oilBiofilmBiofilmTetraclinis articulatachemistryStaphylococcus aureusAntibiofilm activityvisual_artvisual_art.visual_art_mediumAntibacterial activitySawdustAntibacterial activityTP248.13-248.65BiotechnologyCurrent Research in Biotechnology
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Herbicidal value of essential oils from oregano-like flavour species

2017

ABSTRACTChemical composition and phytotoxicity of oregano, marjoram and Thymus mastichina essential oils against Portulaca oleracea L., Lolium multiflorum Lam. and Echinochloa crus-galli (L.) Beauv. has been investigated. Seventy-seven compounds reaching 97.3% and 99.4% were identified by gas chromatography–mass spectrometry. Carvacrol (60.42 ± 0.07%), p-cymene (15.52 ± 0.02%) and γ-terpinene (5.19 ± 0.02%) were the main compounds in oregano essential oil, whereas large amounts of 1,8-cineol (59.59 ± 0.85%, 49.49 ± 0.37%), linalool (13.05 ± 0.04%, 5.66 ± 0.01%) and α-terpineol (3.36 ± 0.10%, 5.59 ± 0.01%), followed by β-pinene (4.35 ± 0.39, 5.54 ± 0.01%) and α-pinene (4.11 ± 0.53, 4.28 ± 0.…

010405 organic chemistryImmunologyThymus mastichinaLolium multiflorumBiologyPortulacabiology.organism_classification01 natural sciences0104 chemical scienceslaw.invention010404 medicinal & biomolecular chemistrychemistry.chemical_compoundLinaloolchemistrylawGerminationBotanyCarvacrolPhytotoxicityFood scienceAgronomy and Crop ScienceEssential oilFood ScienceFood and Agricultural Immunology
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Effect of two phenanthrene alkaloids on angiotensin II-induced leukocyte-endothelial cell interactionsin vivo

2003

The present study has evaluated the effect of two phenanthrene alkaloids, uvariopsine and stephenanthrine, on angiotensin II (Ang-II)-induced leukocyte–endothelial cell interactions in vivo and the mechanisms involved in their activity. Intravital microscopy within the rat mesenteric microcirculation was used. A 60 min superfusion with 1 nM Ang-II induced a significant increase in the leukocyte–endothelial cell interactions that were completely inhibited by 1 μM uvariopsine cosuperfusion. A lower dose of 0.1 μM significantly reduced Ang-II-induced leukocyte adhesion by 75%. When Ang-II was cosuperfused with 1 and 0.1 μM stephenanthrine, Ang-II-induced leukocyte responses were significantly …

Pharmacologychemistry.chemical_classificationmedicine.medical_specialtyReactive oxygen speciesPlatelet-activating factorSuperoxideLeukocyte RollingPharmacologyN-Formylmethionine leucyl-phenylalanineAngiotensin IIEndothelial stem cellchemistry.chemical_compoundEndocrinologychemistryInternal medicinemedicineIntracellularBritish Journal of Pharmacology
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Artemisia arborescens L.: essential oil composition and effects of plant growth stage in some genotypes from Sicily

2012

Essential oils from aerial parts of several Artemisia arborescens L. populations, collected in five different localities of Sicily, were analyzed by gas chromatograph–flame ionization detector (GC–FID) and GC–mass spectrometry (GC–MS) in order to study the chemical composition and its variability due to phenological stage. Forty-three compounds, accounting for more than 92% of the oil, were identified. Monoterpene fraction with the exception of Petru population was higher than the sesquiterpene fraction. β-Thujone (20.5–55.9%), chamazulene (15.2–49.4%), camphor (1.3–10.7%) and germacrene D (2.3–3.4%) were the main compounds. Chemical composition was influenced by phenological stage, with an…

MonoterpeneArtemisia arborescens L.PopulationSesquiterpenephenological stageessential oillaw.inventionchemistry.chemical_compoundCamphorlawcamphorBotanygermacrene DeducationChemical compositionEssential oileducation.field_of_studybiologyChemistryChamazulenechamazuleneGeneral ChemistryArtemisia arborescensbiology.organism_classificationbeta-thujoneSettore AGR/02 - Agronomia E Coltivazioni Erbaceedistillation time
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Effects ofThymus species extracts on rat duodenum isolated smooth muscle contraction

1989

The diethylether, ethylacetate and butanolic extracts from Thymus webbianus and Thymus leptophyllus were tested for spasmolytic activity. Pre-incubation of the isolated rat duodenum with these extracts for 10 min produced a concentration-dependent inhibition of acetylcholine-induced contractions. This effect was at least ten times greater with the apolar extracts than with the polar extracts.

Pharmacologymedicine.medical_specialtyEndocrinologySmooth muscleInternal medicinemedicineRat Duodenumlipids (amino acids peptides and proteins)Smooth muscle contractionBiologyPhytotherapy Research
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Mandarin essential oils inhibit quorum sensing and virulence factors of Pseudomonas aeruginosa

2016

Pseudomonas aeruginosa produces biofilm and several virulence factors coordinated by quorum sensing (QS) in food. The interruption of QS is a target to control the bacterial virulence. Chemical preservatives used to control biofilm give rise to several food safety problems. For this reason, essential oils (EOs), generally recognized as safe products, are a hopeful alternative. The aim of this work was to determine the chemical composition of mandarin EOs obtained by cold-pressing (EOP) and cold-pressing followed by steam distillation (EOPD) and their antipathogenic properties against P. aeruginosa. Both EOs contained the highest quantities of monoterpene hydrocarbons, mainly limonene, follo…

0301 basic medicinePseudomonas aeruginosaOtras Ciencias BiológicasBiofilm030106 microbiologyBiofilmVirulencePseudomonas AeruginosaBiologyAntipathogenicmedicine.disease_causeMicrobiologyCiencias Biológicas//purl.org/becyt/ford/1 [https]03 medical and health sciencesQuorum sensing030104 developmental biologyCitrus Reticulata Essential OilBotanymedicine//purl.org/becyt/ford/1.6 [https]CIENCIAS NATURALES Y EXACTASFood Science
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Phytotoxic effects of commercial essential oils on selected vegetable crops: Cucumber and tomato

2020

Abstract Essential oils of Origanum vulgare L., Rosmarinus officinalis L., Thymus mastichina L., Ocimum basilicum L., Melaleuca alternifolia Maiden & Betche ex Cheel, Eucalyptus globulus Labill., Gaultheria procumbens L. and Origanum majorana L., with herbicidal effects at different doses (0.125, 0.250, 0.50 and 1 μL/mL) were tested against Cucumis sativus L. and Solanum lycopersicum L., in order to ensure their harmlessness against these Mediterranean food crops. Oregano (carvacrol 60.42%) was the most damaging essential oil, exhibiting a dose-dependent phytotoxic activity against the seed germination and seedling growth of cucumber and tomato, whereas rosemary (1,8-cineole 24.95%, camphor…

biology010405 organic chemistryMelaleuca alternifoliaPharmaceutical ScienceOriganumManagement Monitoring Policy and Law010402 general chemistrybiology.organism_classification01 natural sciencesPollution0104 chemical scienceslaw.inventionHorticulturechemistry.chemical_compoundchemistrySeedlinglawRadicleEnvironmental ChemistryCarvacrolBioherbicideCucumisEssential oilSustainable Chemistry and Pharmacy
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Phytotoxicity of Essential Oils on Selected Weeds: Potential Hazard on Food Crops

2018

The chemical composition of winter savory, peppermint, and anise essential oils, and in vitro and in vivo phytotoxic activity against weeds (Portulaca oleracea, Lolium multiflorum, and Echinochloa crus-galli) and food crops (maize, rice, and tomato), have been studied. Sixty-four compounds accounting for between 97.67&ndash

0106 biological sciencesweed controlwinter savoryPlant Sciencephytotoxicity01 natural sciencesArticlelaw.inventionchemistry.chemical_compoundlawlcsh:BotanyCarvacrolThymolessential oilsEcology Evolution Behavior and SystematicsEssential oilpeppermintEcologybiologyfood and beverages04 agricultural and veterinary sciencesLolium multiflorumfood cropsbiology.organism_classificationMenthonelcsh:QK1-989Horticulturechemistry040103 agronomy & agricultureWinter savory0401 agriculture forestry and fisheriesPhytotoxicityWeed010606 plant biology & botanyPlants
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Chemical variability in the essential oil of Cinnamomum tamala L. leaves from India.

2011

The chemical composition of the essential oils obtained from the fresh leaves of Cinnamomum tamala Nees et Eberm. was determined by GC and GC–MS. The yield of the oil on a dry weight basis ranged from 1.2% to 3.9% (w/w). Phenyl propanoids constitute the major portion (88.9–95.0%) of the oils. Fifty-four compounds were identified from the oils. Eugenol (91.4–41.8%) was the main compound, followed by eugenyl acetate (0.0–47.1%) and α-phellandrene (0.6–2.5%) in the analysed oils.

food.ingredientIndiaPlant ScienceBiochemistryGas Chromatography-Mass SpectrometryAnalytical Chemistrylaw.inventionchemistry.chemical_compoundfoodDry weightlawBotanyOils VolatileFood scienceChemical compositionEssential oilCinnamomumbiologyOrganic ChemistryLauraceaebiology.organism_classificationEugenolPlant LeaveschemistryEugenyl acetateGas chromatography–mass spectrometryCinnamomum tamalaNatural product research
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Herbicidal Activity of Peumus boldus and Drimys winterii Essential Oils from Chile

2011

[EN] The essential oil composition of Peumus boldus and Drimys winterii was analyzed by means of capillary GC-FID and GC-MS. More than 96% of the total oil components (43 and 54 compounds, respectively) were identified, with ascaridole (51.17 ± 9.51), p-cymene (16.31 ± 2.52) and 1,8-cineole (14.45 ± 2.99) as the main compounds in P. boldus and ¿-eudesmol (21.65 ± 0.41), followed of elemol (12.03 ± 0.34) and terpinen-4-ol (11.56 ± 1.06) in D. winterii. The herbicidal activity was tested against Amaranthus hybridus and Portulaca oleracea. P. boldus essential oil was the most phytotoxic against both weeds, inhibiting seed germination and seedling growth at all concentrations assayed (0.125-1 ¿…

DrimysChromatography GasAmaranthus hybridusBOTANICAPharmaceutical ScienceGerminationPortulacaEssential oilArticleAnalytical Chemistrylaw.inventionlcsh:QD241-441chemistry.chemical_compoundlcsh:Organic chemistrylawDrug DiscoveryBotanyOils VolatilePhysical and Theoretical ChemistryChileSeedling growthEssential oilBIOLOGIA VEGETALGas chromatographybiologyMass spectrometryHerbicidesOrganic Chemistrybiology.organism_classificationDrimysChemistrychemistryIsolation and purificationChemistry (miscellaneous)GerminationSeedlingEssential oilsPhytotoxicityPeumusMonoterpenesMolecular MedicinePhytotoxicityHerbicideAscaridoleessential oils; phytotoxicity; germination; seedling growth; monoterpenesPeumus boldus
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Herbicidal activity of Thymbra capitata (L.) Cav. essential oil

2020

The bioherbicidal potential of Thymbra capitata (l.) Cav. essential oil (EO) and its main compound carvacrol was investigated. In in vitro assays, the EO blocked the germination and seedling growth of Erigeron canadensis L., Sonchus oleraceus (l.) L., and Chenopodium album L. at 0.125 &micro

0106 biological sciencesAvenaPharmaceutical ScienceIntegrated weed managementSolanum nigrum3101.06 Herbicidas01 natural sciencesAnalytical Chemistrylaw.inventionchemistry.chemical_compoundbioherbicideslawDrug Discovery2302.10 Aceites Esencialesnatural herbicidesCarvacrol0303 health sciencesSetaria verticillatabiologyChenopodium3103.15 Control de MalezasWeed controlSettore AGR/02 - Agronomia E Coltivazioni Erbacee02.- Poner fin al hambre conseguir la seguridad alimentaria y una mejor nutrición y promover la agricultura sostenibleHorticultureChemistry (miscellaneous)Essential oilsintegrated weed managementMolecular Medicineweed controlSettore AGR/13 - Chimica AgrariaBOTANICAcarvacrolPortulacanatural herbicideThymbra capitataessential oilArticlelcsh:QD241-44103 medical and health sciencesBioherbicideslcsh:Organic chemistryCarvacrolOils VolatilePhysical and Theoretical ChemistryAvena fatuaessential oilsEssential oil030304 developmental biologyLamiaceaeHerbicidesOrganic Chemistrybiology.organism_classificationSonchus oleraceuschemistrySeedlingsEchinochloaCapitataNatural herbicides010606 plant biology & botany
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