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RESEARCH PRODUCT
Effects ofThymus species extracts on rat duodenum isolated smooth muscle contraction
María Amparo BlázquezM. C. Zafra-poloAngel Villarsubject
Pharmacologymedicine.medical_specialtyEndocrinologySmooth muscleInternal medicinemedicineRat Duodenumlipids (amino acids peptides and proteins)Smooth muscle contractionBiologydescription
The diethylether, ethylacetate and butanolic extracts from Thymus webbianus and Thymus leptophyllus were tested for spasmolytic activity. Pre-incubation of the isolated rat duodenum with these extracts for 10 min produced a concentration-dependent inhibition of acetylcholine-induced contractions. This effect was at least ten times greater with the apolar extracts than with the polar extracts.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1989-01-01 | Phytotherapy Research |