0000000000929568
AUTHOR
M. C. Zafra-polo
Further Flavonoids and Other Phenolics of Thymus webbianus Rouy
Abstract Seven different flavonoids from the aerial parts of Thymus webbianus were isolated. They were identified by UV spectra, TLC and HPLC-DAD as luteolin, apigenin, eryodictiol, naringenin, luteolin-7-O-glucoside, apigenin-7-O-glucoside and apigenin-6,8-di-C-glucoside. Other phenolics characterized by HPLC-DAD analysis were: protocatechuic, chlorogenic, syringic, p-coumaric and 3,5-dicaffeoylquinic acids.
Effects ofThymus species extracts on rat duodenum isolated smooth muscle contraction
The diethylether, ethylacetate and butanolic extracts from Thymus webbianus and Thymus leptophyllus were tested for spasmolytic activity. Pre-incubation of the isolated rat duodenum with these extracts for 10 min produced a concentration-dependent inhibition of acetylcholine-induced contractions. This effect was at least ten times greater with the apolar extracts than with the polar extracts.