6533b7d4fe1ef96bd12632e5

RESEARCH PRODUCT

Chromone and phenanthrene alkaloids from Dennettia tripetala.

Maria-jesus SanzMaría Amparo BlázquezHerminio BoiraJavier López-martínEdet M. Anam

subject

Magnetic Resonance SpectroscopyTertiary amineStereochemistryAnnonaceaePharmacognosyPlant RootsStephenanthrinechemistry.chemical_compoundAlkaloidsDrug DiscoveryOrganic chemistrySpectroscopyDennettia tripetalabiologyMolecular StructureVanillinUvariopsineGeneral ChemistryGeneral MedicineNuclear magnetic resonance spectroscopyPhenanthrenePhenanthrenesbiology.organism_classificationchemistryHeteronuclear moleculeAnnonaceaeChromonesChromone

description

Dennettine, a new 2,6-dimethoxychromone and three known phenanthrene alkaloids (uvariopsine, stephenanthrine and argentinine) in addition to the phenolic and known compound vanillin were isolated from the roots of Dennettia tripetala. Their structures were determined by physical and spectroscopical one dimensional (1D) and 2D-NMR analysis, including heteronuclear multiple bond correlation and nuclear Overhauser enhancement spectroscopy.

10.1248/cpb.50.1613https://pubmed.ncbi.nlm.nih.gov/12499602