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RESEARCH PRODUCT

Patterns and trends in scientific research on generic drugs

Rut Lucas-dominguezAdolfo Alonso-arroyoJuan Carlos Valderrama-zuriánCarolina NavarroAntonio Vidal-inferRafael Aleixandre-benavent

subject

Drugmedicine.medical_specialtyATC classification systemmedia_common.quotation_subjectAlternative medicineMEDLINEPharmacology030226 pharmacology & pharmacy03 medical and health sciences0302 clinical medicineAntithromboticmedicineDrugs GenericHumansGeneric drugsPharmacology (medical)030212 general & internal medicineIntensive care medicinemedia_commonPharmacologyPeer Review Researchbusiness.industryResearchDrugs genericPubMed/MedlinePeriodicals as TopicMedline databasebusinessContent analysis

description

[Purpose]: The purpose of this study to investigate the evolution and current status of peer-reviewed publications concerning generic drugs during the past few decades. [Methods]: Scientific articles about generic drugs published until 2012 were retrieved through the PubMed/MEDLINE database, and a content analysis was performed. [Findings]: Our study revealed an increasing number of publications on generics since 1984. Statins, antiretroviral therapies, and antiepileptics, followed by immunosuppressants and antithrombotic agents, were the most common therapeutic drug categories. [Implications]: Almost 60% of the generics detailed in studies indexed in MEDLINE were acting on the cardiovascular system as anti-infectives and on the nervous system, which is not surprising considering the leading causes of death and disability worldwide.

yearjournalcountryeditionlanguage
2016-01-01
10.1016/j.clinthera.2016.10.010http://hdl.handle.net/10261/161538