6533b83afe1ef96bd12a704d

RESEARCH PRODUCT

A diagnostic trap for the dermatopathologist: granulomatous reactions from cutaneous microimplants for cosmetic purposes.

M. I. MinerviniS. AmatoElisabetta BarresiVincenzo MustacchioDaniela Cabibi

subject

medicine.medical_specialtyPathologyHistologyPathology SurgicalInjections SubcutaneousSiliconesCosmetic TechniquesDermatologyLiposarcomaSettore MED/08 - Anatomia PatologicaPathology and Forensic Medicinegranuloma silicone liposarcoma granulomatous reaction skinInjection siteMedicineHumansSkinbusiness.industryGranuloma Foreign-BodyUpper lipAnatomical pathologyProstheses and ImplantsMiddle Agedmedicine.diseaseDermatologyImmunohistochemistrySurgerystomatognathic diseasesGranulomaFaceFemaleForeign bodybusinessBiomarkers

description

We present a case of late granulomatous reactions from silicone that first appeared in a site different from that of the injection causing an incorrect diagnosis of liposarcoma in the beginning. The histological picture was a cystic-macrophagic granuloma in both the injection site (upper lip) and the migrating site (paranasal regions). We think that the foreign body has undergone an antigravity migration from the upper lip to the right paranasal region. To our knowledge, such a phenomenon has not been yet reported in literature.

yearjournalcountryeditionlanguage
2007-01-01Journal of cutaneous pathology
10.1111/j.1600-0560.2006.00607.xhttps://pubmed.ncbi.nlm.nih.gov/17302614