6533b83afe1ef96bd12a79a8

RESEARCH PRODUCT

Thymic transplantation for relief of immunodeficiency diseases.

Sheldon D. HorowitzHermann Schulte-wissermannRichard Hong

subject

business.industryImmunologic Deficiency SyndromesInfantMice NudeThymus Glandmedicine.diseaseLiver TransplantationTransplantationMicesurgical procedures operativeFetusCulture TechniquesImmunologymedicineAnimalsHumansSurgeryTransplant patientFemaleRabbitsbusinessImmunodeficiency

description

Tremendous advances have been made in replacement therapy regimens for the correction of immunodeficiency in transplant patients. Recently, cultured thymic fragments were shown to be devoid of lethal graft-versus-host cells and research in this area indicates that thymic transplantation may have a sustained positive effect in immunosuppressed patients.

10.1016/s0039-6109(16)41786-xhttps://pubmed.ncbi.nlm.nih.gov/375446