6533b851fe1ef96bd12a975e

RESEARCH PRODUCT

Effekt von Calcium und Magnesium auf die Parathormonfreisetzung aus humanem Parathyreoidea-Gewebe in vitro

U. KrauseM. RothmundP. K. Wagner

subject

medicine.medical_specialtyHyperparathyroidismendocrine system diseasesAdenomaParathyroid neoplasmchemistry.chemical_elementParathyroid hormoneGeneral MedicineCalciummedicine.diseaseEndocrinologychemistryInternal medicinemedicineSecondary hyperparathyroidismPrimary hyperparathyroidismHormone

description

The effects of calcium and magnesium on parathyroid hormone release from eight adenomas causing primary hyperparathyroidism and six hyperplastic glands causing hypercalcemic secondary hyperparathyroidism were investigated in vitro using single cell suspensions from the respective tissue. We observed suppression of parathyroid hormone release with increasing concentrations of either cation. The quantitative hormone secretions of both adenomatous and hyperplastic glands was identical.

https://doi.org/10.1007/bf01851191