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RESEARCH PRODUCT

Orofacial features and medical profile of eight individuals with Kabuki syndrome

Karem López-ortegaMarina GallottiniNatália Silva-andrade

subject

Pediatricsmedicine.medical_specialtyAdolescentCleft LipDental CariesAnodontia03 medical and health sciences0302 clinical medicinemedicineMicrodontiaHumansAbnormalities MultipleCraniofacialFamily historyChildGeneral DentistryAnodontiaRetrospective StudiesTooth Abnormalitiesbusiness.industryResearch030206 dentistryEnamel hypoplasia:CIENCIAS MÉDICAS [UNESCO]Medically compromised patients in Dentistrymedicine.diseaseHematologic DiseasesCleft Palatestomatognathic diseasesOtitisVestibular DiseasesOtorhinolaryngologyChild PreschoolFaceAgenesisUNESCO::CIENCIAS MÉDICASSurgerymedicine.symptombusinessKabuki syndrome

description

Background To evaluate oral, craniofacial and systemic characteristics of eight patients with Kabuki syndrome (KS), aged between 3 and 16 years old. Material and Methods In this retrospective study, medical records of all patients were reviewed for information on family history, growth and development, medications in use, general systemic complications and oral and craniofacial characteristics. Results The medical alterations found included recurrent infections such as pneumonia and otitis media (n = 6), cardiovascular malformations (n = 4), kidney abnormalities (n = 2), epilepsy (n = 2) and visual deficiency (n = 2). The individuals exhibited dental caries (n = 5), agenesis (n = 5), delayed tooth eruption (n = 4), cleft lip/palate (n = 2) enamel hypoplasia (n = 2), fusion (n = 1) and microdontia (n = 1). Conclusions There was a great diversity of oral, craniofacial and systemic characteristic among the KS patients, suggesting that an inter-disciplinary approach should be taken for their dental treatment. Key words:Kabuki syndrome, oral manifestations, medical alterations.

yearjournalcountryeditionlanguage
2019-08-01Medicina Oral Patología Oral y Cirugia Bucal
https://doi.org/10.4317/medoral.22982