6533b851fe1ef96bd12aa0a2
RESEARCH PRODUCT
ChemInform Abstract: A Theoretical Study of the Selectivity for the Domino [5 + 2]/[4 + 2] Cycloadditions of γ-Pyrones Bearing Tethered Alkenes with Substituted 1,3-Butadienes.
Ramón J. ZaragozáLuis R. Domingosubject
chemistry.chemical_classificationBearing (mechanical)chemistryAlkenelawOrganic chemistryGeneral MedicineChemoselectivitySelectivityMedicinal chemistryCycloadditionDominolaw.inventiondescription
Abstract Selectivity of the domino [5+2]/[4+2] cycloaddition reactions of a β-silyloxy-γ-pyrone bearing a tethered alkene with two substituted 1,3-butadienes have been theoretically studied at the B3LYP/6-31G∗//AM1 and B3LYP/6-31G∗ computational levels. Analysis of these results allow explaining the regio, stereo and chemoselectivity observed experimentally at these domino reactions. Selectivity outcome is reproduced by these calculations.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2010-05-24 | ChemInform |