6533b852fe1ef96bd12aa49b
RESEARCH PRODUCT
Abyssomicin E, a highly functionalized polycyclic metabolite from Streptomyces species.
Dieter SchollmeyerXue-mei NiuSusanne GrableyHelmar GörlsMatthias HilligerSheng-hong LiIsabel Sattlersubject
Models MolecularbiologyMolecular StructureChemistryStereochemistryChemical structureMetaboliteOrganic ChemistryGeneral MedicineAbyssomicin Ebiology.organism_classificationBridged Bicyclo Compounds HeterocyclicBiochemistryStreptomycesStreptomyces speciesStreptomyceschemistry.chemical_compoundOrganic chemistryPhysical and Theoretical Chemistrydescription
Abyssomicin E (1), a new polycyclic metabolite with a C19 skeleton, was isolated from Streptomyces sp. (HKI0381). Its chemical structure was determined by comprehensive NMR and MS spectroscopic analyses. For the first time in this recently discovered class of compounds, the absolute stereochemistry was directly established by subsequent single-crystal X-ray diffraction study using anomalous dispersion with copper radiation.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2007-05-25 | Organic letters |