6533b852fe1ef96bd12aab3c

RESEARCH PRODUCT

Capacity of Gentamicin-Treated Pseudomonas aeruginosa to Induce Granulocyte Locomotion

M. P. DierichW. Weikel

subject

Granulocyte migrationPseudomonas aeruginosaChemistryChemotaxisBoyden chamberGranulocytemedicine.disease_causeMicrobiologyMinimum inhibitory concentrationmedicine.anatomical_structuremedicineParasite hostingGentamicinmedicine.drug

description

In protection against an invading parasite the host’s granulocytes play an essential role. To exert their defense the phagocytes have to be attracted to the site of parasite invasion. We have shown that Pseudomonas aeruginosa ATCC 27853 and other clinical isolates of this species can induce granulocyte migration, either directly or via generation of chemotactic activity in serum [1].

https://doi.org/10.1007/978-3-642-68670-2_15