The DAT ligand [(18)F]PR17.MZ mirrors the in vivo pharmacokinetic profile of [(11)C]cocaine with significantly improved monoamine transporter selectivity.

6533b852fe1ef96bd12aaf3d

RESEARCH PRODUCT

The DAT ligand [(18)F]PR17.MZ mirrors the in vivo pharmacokinetic profile of [(11)C]cocaine with significantly improved monoamine transporter selectivity.

Vanessa Bockhart Hans-georg Buchholz Markus Piel Patrick J. Riss Patrick J. Riss Hartmut Lueddens Nicole Bausbacher Frank Roesch

subject

Fluorine Radioisotopes Contrast Media Pharmacology Ligands Biochemistry Rats Sprague-Dawley Pharmacokinetics Cocaine In vivo Drug Discovery medicine Animals Biogenic Monoamines Carbon Radioisotopes General Pharmacology Toxicology and Pharmaceutics Dopamine transporter Pharmacology Dopamine Plasma Membrane Transport Proteins Monoamine transporter biology medicine.diagnostic_test Chemistry Organic Chemistry Ligand (biochemistry)Rats Biochemistry Positron emission tomography Positron-Emission Tomography biology.protein Molecular Medicine Radiopharmaceuticals Selectivity

year	journal	country	edition	language
2010-09-09	ChemMedChem

10.1002/cmdc.201000237 https://pubmed.ncbi.nlm.nih.gov/20830722

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