6533b852fe1ef96bd12ab69b
RESEARCH PRODUCT
Mitochondrial DNA evolution in experimental populations of Drosophila subobscura.
Amparo LatorreM FosM A DomínguezAndrés Moyasubject
GeneticsCell NucleusMitochondrial DNAeducation.field_of_studyMultidisciplinaryHaplotypePopulationPopulation geneticsGenetic VariationBiologyBiological EvolutionDNA MitochondrialDrosophila subobscuraFixation (population genetics)Genetics PopulationGenetic driftHaplotypesEvolutionary biologyGenetic variationChromosome InversionAnimalsDrosophilaeducationResearch Articledescription
When two mitochondrial DNA (mtDNA) haplotypes of Drosophila subobscura compete in experimental populations with discrete generations, one or the other approaches fixation, depending on the nuclear background with which they are associated. The approach to fixation, however, is strongly dependent on the effective number of females in the population, Nf. Whether or not the ultimate fate of a given mtDNA haplotype is determined by random genetic drift depends on Nf as well as on the relative fitnesses. Our experimental results show that the mtDNA polymorphisms observed in natural populations are affected by interactions among nuclear polymorphisms, random genetic drift, and direct selection on the mtDNA haplotypes.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1990-06-01 |