6533b852fe1ef96bd12ab906
RESEARCH PRODUCT
New Alkenylresorcinols with Cytotoxic and Antimicrobial Activities from the Leaves of Embelia schimperi.
Blanche Laure NdontsaPierre TaneTatiana Arlette M. TogueMathieu TeneGabin Thierry M. BitchagnoGabin Thierry M. BitchagnoTill OpatzAnja Schüfflersubject
EmbeliaPhytochemicalsPharmaceutical ScienceEmbelia01 natural sciencesAnalytical ChemistryAnti-Infective AgentsDrug DiscoveryCytotoxic T cellHumansCytotoxicityPharmacologyTraditional medicinebiology010405 organic chemistryChemistryPlant ExtractsOrganic ChemistryIsolation (microbiology)biology.organism_classificationAntimicrobial0104 chemical sciencesPlant Leaves010404 medicinal & biomolecular chemistryPrimulaceaeComplementary and alternative medicinePhytochemicalMolecular MedicineBacteriadescription
AbstractA phytochemical study of the methanol extract of the leaves of Embelia schimperi resulted in the isolation of three new alkenylresorcinols, 1 – 3, together with the known analogs 4 – 7. Their structures were established by a combination of spectroscopic techniques. Compounds 1 – 7 exhibited moderate cytotoxic activity against human cervical cancer cells HeLa-S3 and more pronounced antimicrobial properties towards bacteria and filamentous fungi. The present study falls into an ongoing research project on the characterization of bioactive phenolic lipids from plants of the family Primulaceae.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2020-07-29 | Planta medica |