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RESEARCH PRODUCT
Fluorescent metal-based complexes as cancer probes.
Riccardo BonsignoreAndreia De Almeidasubject
LightClinical BiochemistryPharmaceutical ScienceAntineoplastic Agents01 natural sciencesBiochemistryMetal-based probesMetalMetal complexesCoordination ComplexesCell Line TumorMetals HeavyNeoplasmsDrug DiscoveryAnticancer probesFluorescence microscopemedicineAnimalsHumansSolubilityMolecular BiologyFluorescent DyesFluorescence microscopyTargeting010405 organic chemistryChemistryOrganic ChemistryCancermedicine.diseaseTheranosticsCombinatorial chemistryFluorescence0104 chemical sciences010404 medicinal & biomolecular chemistryvisual_artvisual_art.visual_art_mediumFluorescent probesMolecular Medicinedescription
Abstract The ability to track drugs inside of cells and tumours has been highly valuable in cancer research and diagnosis. Metal complexes add attractive features to fluorescent drugs, such as targeting and specificity, solubility and uptake or photophysical properties. This review focuses on the latest fluorescent metal-based complexes, their cellular targets, photophysical properties and possible anticancer effects.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2020-02-28 | Bioorganicmedicinal chemistry letters |