6533b853fe1ef96bd12abff5

RESEARCH PRODUCT

Appetite and Obesity

Alice EngelNorbert Dahmen

subject

medicine.medical_specialtyLateral hypothalamusbusiness.industrymedia_common.quotation_subjectdigestive oral and skin physiologyAppetitemedicine.diseaseOrexin receptorOrexinEndocrinologymedicine.anatomical_structurenervous systemHypothalamusInternal medicinemental disordersmedicineWakefulnessPeriventricular nucleusbusinesshormones hormone substitutes and hormone antagonistspsychological phenomena and processesNarcolepsymedia_common

description

Orexin (hypocretin) plays an important role in promoting wakefulness [1]. It stimulates wakefulness when injected in the cerebral ventricles, in the periventricular nucleus, dorsomedial hypothalamus, or lateral hypothalamus [2, 3]. Orexinergic neurons originate from the lateral hypothalamus and have projections to most parts of the central nervous system including the brain stem. The lack of orexin and/or orexin receptors is linked to narcolepsy [4–6].

yearjournalcountryeditionlanguage
2011-01-01
https://doi.org/10.1007/978-1-4419-8390-9_21