6533b853fe1ef96bd12accf5
RESEARCH PRODUCT
Pain-induced alterations in the individual non-esterified fatty acids in serum.
R. KnitzaR. ClasenF. Fischersubject
AdultMalemedicine.medical_specialtyIncreased LipolysisAdipose tissueBiologyFatty Acids NonesterifiedTrigeminal ganglionTrigeminal neuralgiaInternal medicinemedicineIdiopathic trigeminal neuralgiaElectrocoagulationHumansLipaseAgedchemistry.chemical_classificationLipid MobilizationFatty acidMiddle AgedTrigeminal Neuralgiamedicine.diseaseGanglionAnesthesiology and Pain MedicineEndocrinologymedicine.anatomical_structureNeurologychemistryTrigeminal Ganglionbiology.proteinFemaleNeurology (clinical)description
Changes of individual non-esterified fatty acids in serum were studied in 7 metabolically healthy patients, suffering from idiopathic trigeminal neuralgia, who underwent electrocoagulation of gasserian ganglion under neurolepthypalgesia. The mean concentration of fatty acids increased by about 40% during the strong surgical pain stimulus. The increased lipolysis affected all individual fatty acids in proportion to the ratio of their presence in adipose tissue. The mechanism of pain-induced activation of lipase and possible consequences of alterations in individual non-esterified fatty acids are discussed.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1979-02-01 | Pain |