Search for New Phenomena in Final States with Two Leptons and One or No b -Tagged Jets at s=13  TeV Using the ATLAS Detector

A search for new phenomena is presented in final states with two leptons and one or no $b$-tagged jets. The event selection requires the two leptons to have opposite charge, the same flavor (electrons or muons), and a large invariant mass. The analysis is based on the full Run-2 proton-proton collision dataset recorded at a center-of-mass energy of $\sqrt{s} = 13$ TeV by the ATLAS experiment at the LHC, corresponding to an integrated luminosity of 139 fb$^{-1}$. No significant deviation from the expected background is observed in the data. A four-fermion contact interaction between two quarks ($b,s$) and two leptons ($ee$ or $\mu\mu$), inspired by the $B$-meson decay anomalies, is used as a…

Global age-sex-specific fertility, mortality, healthy life expectancy (HALE), and population estimates in 204 countries and territories, 1950–2019: a comprehensive demographic analysis for the Global Burden of Disease Study 2019

Background Accurate and up-to-date assessment of demographic metrics is crucial for understanding a wide range of social, economic, and public health issues that affect populations worldwide. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 produced updated and comprehensive demographic assessments of the key indicators of fertility, mortality, migration, and population for 204 countries and territories and selected subnational locations from 1950 to 2019. Methods 8078 country-years of vital registration and sample registration data, 938 surveys, 349 censuses, and 238 other sources were identified and used to estimate age-specific fertility. Spatiotemporal Gaussian…

Optischer Test zur Bestimmung der alkalischen Phosphatase im Serum

Es wird eine neue Bestimmungs-methode fur die Aktivitat der alkalischen Phosphatase im Serum beschrieben, die Phospho-enol-pyruvat als Substrat benutzt. Durch Enzymwirkung freigesetztes Pyruvat wird zu Lactat hydriert und dieser Vorgang im Spektrophotometer verfolgt. Die Eigenschaften dieses optischen Tests werden eingehend diskutiert.

Global, regional, and national progress towards Sustainable Development Goal 3.2 for neonatal and child health: all-cause and cause-specific mortality findings from the Global Burden of Disease Study 2019

Background: Sustainable Development Goal 3.2 has targeted elimination of preventable child mortality, reduction of neonatal death to less than 12 per 1000 livebirths, and reduction of death of children younger than 5 years to less than 25 per 1000 livebirths, for each country by 2030. To understand current rates, recent trends, and potential trajectories of child mortality for the next decade, we present the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 findings for all-cause mortality and cause-specific mortality in children younger than 5 years of age, with multiple scenarios for child mortality in 2030 that include the consideration of potential effects of COVID-…

Erfahrungen bei der Behandlung von 300 akut Alkoholvergifteten

Wie in anderen Landern nimmt auch in Deutschland in den letzten Jahren der Verbrauch alkoholischer Getranke standig zu. Nach amerikanischen Statistiken steht die Alkoholvergiftung als Todesursache bei den Intoxikationen an zweiter Stelle.

Vorsichtsmaßnahmen bei der Anwendung von kolloidalen Vollblutersatzmitteln

Klinische Erfahrungen mit dem Vena Cava-Katheter

Eine intravenose Ernahrung uber langere Zeit ist auserordentlich erschwert durch die nach Tagen, ja sogar nach Stunden auftretenden Venenthrombosen und Phlebitiden, die durch die venenwandschadigende Wirkung hochprozentiger Losungen ausgelost werden. Wir sehen in der Anwendung des Vena cava-Katheters eine Losung dieses Problems, weil die intravenos zugefuhrten Losungen im groseren und schnelleren Blutstrom nicht direkt mit der Venenwand in Beruhrung kommen.

Performance of the upgraded PreProcessor of the ATLAS Level-1 Calorimeter Trigger

The PreProcessor of the ATLAS Level-1 Calorimeter Trigger prepares the analogue trigger signals sent from the ATLAS calorimeters by digitising, synchronising, and calibrating them to reconstruct transverse energy deposits, which are then used in further processing to identify event features. During the first long shutdown of the LHC from 2013 to 2014, the central components of the PreProcessor, the Multichip Modules, were replaced by upgraded versions that feature modern ADC and FPGA technology to ensure optimal performance in the high pile-up environment of LHC Run 2. This paper describes the features of the newMultichip Modules along with the improvements to the signal processing achieved.

Magnetic field controlled FZ single crystal growth of intermetallic compounds

Abstract Intermetallic rare-earth-transition-metal compounds with their coexistence of magnetic ordering and superconductivity are still of great scientific interest. The crystal growth of bulk single crystals is very often unsuccessful due to an unfavorable solid–liquid interface geometry enclosing concave fringes. The aim of the work is the contactless control of heat and material transport during floating-zone single crystal growth of intermetallic compounds. This control is provided by a tailored design of the electromagnetic field and the resulting electromagnetically driven convection. Numerical simulations for the determination of the electromagnetic field configuration induced by th…

Regional Cerebral Blood Flow in Cases of Brain Tumor

The present series consists of 21 patients with brain tumors: 12 malignant gliomas, 4 oligo- dendro gliomas, 3 meningeomas and 2 metastases, studied by the133Xe-gamma-clearance rCBF method. In 16 patients at least 3 determinations of rCBF were performed: a) in the resting state, R; b) during hyperventilation, HV, and c) during hypertension, HT. Of the remaining 5 patients, 1 was studied only during R, while the other 4 were submitted either to HV or to HT additionally to the R study. The average age of this series of patients was 47 years, the youngest being 19 and the oldest 64. rCBF studies had to be performed under general anesthesia (N2O + O2, Engstrom respirator) in 5 instances in whic…

Abstracts from the 1st International Symposium on Decision Support in Anaesthesia and Intensive Care

Observation and Measurement of Forward Proton Scattering in Association with Lepton Pairs Produced via the Photon Fusion Mechanism at ATLAS

The observation of forward proton scattering in association with lepton pairs (eþe− þ p or μþμ− þ p) produced via photon fusion is presented. The scattered proton is detected by the ATLAS Forward Proton spectrometer, while the leptons are reconstructed by the central ATLAS detector. Proton-proton collision data recorded in 2017 at a center-of-mass energy of ffiffiffi s p ¼ 13 TeV are analyzed, corresponding to an integrated luminosity of 14.6 fb−1. A total of 57 (123) candidates in the ee þ p (μμ þ p) final state are selected, allowing the background-only hypothesis to be rejected with a significance exceeding 5 standard deviations in each channel. Proton-tagging techniques are introduced f…

Über die Anwendung des Vena cava-Katheters aus klinischer und pathologisch-anatomischer Sicht

Es wird uber die Erfahrungen mit 150 Cava-Kathetern bei 130 neurochirurgischen Patienten berichtet unter Besprechung der Befunde aus 21 Obduktionsfallen. Auf das grosere Risiko bei Verwendung der Venen der unteren Extremitaten und der Vena cava caudalis wird eingegangen, die eigene Methode des Einlegens eines Katheters in die Vena cava cranialis von der Vena basilica her geschildert und auf mogliche technische Fehler aufmerksam gemacht. Als Komplikationen im klinischen Verlauf wurden 14mal eine Thrombophlebitis, 12mal eine Verstopfung und zehnmal ein unbeabsichtigtes Herausziehen des Katheters registriert. Ernste Komplikationen wurden klinisch nicht beobachtet. Demgegenuber zeigten die Obdu…

Pain-induced alterations in the individual non-esterified fatty acids in serum.

Changes of individual non-esterified fatty acids in serum were studied in 7 metabolically healthy patients, suffering from idiopathic trigeminal neuralgia, who underwent electrocoagulation of gasserian ganglion under neurolepthypalgesia. The mean concentration of fatty acids increased by about 40% during the strong surgical pain stimulus. The increased lipolysis affected all individual fatty acids in proportion to the ratio of their presence in adipose tissue. The mechanism of pain-induced activation of lipase and possible consequences of alterations in individual non-esterified fatty acids are discussed.

Correlation between rCBF, Angiography, EEG and Scanning in Brain Tumors

The findings with techniques of different sensitivity, and which investigate different aspects of brain structure and/or function are difficult to correlate. However, such a comparison should help in elucidating the physiopathological mechanisms of brain lesions and the postoperative clinical evolution and prognosis in cases of brain tumors.

Five insights from the Global Burden of Disease Study 2019

The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 provides a rules-based synthesis of the available evidence on levels and trends in health outcomes, a diverse set of risk factors, and health system responses. GBD 2019 covered 204 countries and territories, as well as first administrative level disaggregations for 22 countries, from 1990 to 2019. Because GBD is highly standardised and comprehensive, spanning both fatal and non-fatal outcomes, and uses a mutually exclusive and collectively exhaustive list of hierarchical disease and injury causes, the study provides a powerful basis for detailed and broad insights on global health trends and emerging challenges. GBD …

Subnational mapping of HIV incidence and mortality among individuals aged 15-49 years in sub-Saharan Africa, 2000-18: a modelling study

Background. High-resolution estimates of HIV burden across space and time provide an important tool for tracking and monitoring the progress of prevention and control efforts and assist with improving the precision and efficiency of targeting efforts. We aimed to assess HIV incidence and HIV mortality for all second-level administrative units across sub-Saharan Africa. Methods. In this modelling study, we developed a framework that used the geographically specific HIV prevalence data collected in seroprevalence surveys and antenatal care clinics to train a model that estimates HIV incidence and mortality among individuals aged 15–49 years. We used a model-based geostatistical framework to e…

Technical challenges in the construction of the steady-state stellarator Wendelstein 7-X

The next step in the Wendelstein stellarator line is the large superconducting device Wendelstein 7-X, currently under construction in Greifswald, Germany. Steady-state operation is an intrinsic feature of stellarators, and one key element of the Wendelstein 7-X mission is to demonstrate steady-state operation under plasma conditions relevant for a fusion power plant. Steady-state operation of a fusion device, on the one hand, requires the implementation of special technologies, giving rise to technical challenges during the design, fabrication and assembly of such a device. On the other hand, also the physics development of steady-state operation at high plasma performance poses a challeng…

The overlapping burden of the three leading causes of disability and death in sub-Saharan African children

Publisher Copyright: © 2022, The Author(s). Despite substantial declines since 2000, lower respiratory infections (LRIs), diarrhoeal diseases, and malaria remain among the leading causes of nonfatal and fatal disease burden for children under 5 years of age (under 5), primarily in sub-Saharan Africa (SSA). The spatial burden of each of these diseases has been estimated subnationally across SSA, yet no prior analyses have examined the pattern of their combined burden. Here we synthesise subnational estimates of the burden of LRIs, diarrhoea, and malaria in children under-5 from 2000 to 2017 for 43 sub-Saharan countries. Some units faced a relatively equal burden from each of the three diseas…

�ber den Einflu� vegetativ wirksamer Pharmaka auf die Folgen der Injektion von Thiopental in die Arteria femoralis der Ratte

An 150 Ratten wurde der Einflus vegetativ wirksamer Pharmaka (Reserpin, Guanethidin, Chlorisondamin, Dibenamin, Atropin, Hydroxyphenylaminoathanol) auf die Folgen einer Injektion von Thiopental in die Femoralarterie untersucht. Keine der gepruften Substanzen verminderte die durch Thiopental verursachten lokalen Schadigungen.

Stellenwert der Inhalationsanästhetika in der Neuroanästhesie - Eine Betrachtung der „Nebenwirkungen”