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RESEARCH PRODUCT
Algorithm for the management of patients at low, high and very high risk of osteoporotic fractures
Joon Kiong LeeKenneth G. SaagWeibo XiaO. MkinsiF. JiwaHelena JohanssonHelena JohanssonDaniel Prieto-alhambraDaniel Prieto-alhambraEnwu LiuNicholas C. HarveyMattias LorentzonMattias LorentzonMattias LorentzonC. CampusanoBess Dawson-hughesOlivier BruyèreDaniel PintoDaniel PintoNicola VeroneseCyrus CooperCyrus CooperRené RizzoliL. ZakraouiJean-yves ReginsterJean-yves ReginsterManju ChandranKassim JavaidNasser M. Al-daghriEugene V. MccloskeyEugene V. MccloskeyDemetrio MessinaGemma AdibJ. A. KanisJ. A. Kanissubject
0301 basic medicinemedicine.medical_specialtyFRAXEndocrinology Diabetes and MetabolismeducationOsteoporosisPsychological interventioninhibitors of bone resorption030209 endocrinology & metabolismRisk AssessmentAnabolic agents03 medical and health sciencesTherapeutic approach0302 clinical medicineBone DensityRisk FactorsTreatment of osteoporosisInternal medicinemedicinefracture risk assessmentHumansanabolic agentsIntensive care medicineOsteoporosis PostmenopausalAgedAnabolic agents Fracture risk assessment FRAX Inhibitors of bone resorption Treatment of osteoporosisddc:616Postmenopausal womenbusiness.industryCorrectionFracture risk assessmentInhibitors of bone resorptionMiddle Agedtreatment of osteoporosismedicine.diseaseRheumatologyIncreased riskFemalePosition Paper030101 anatomy & morphologybusinessVery high riskAlgorithmsOsteoporotic FracturesFRAXdescription
Summary Guidance is provided in an international setting on the assessment and specific treatment of postmenopausal women at low, high and very high risk of fragility fractures. Introduction The International Osteoporosis Foundation and European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis published guidance for the diagnosis and management of osteoporosis in 2019. This manuscript seeks to apply this in an international setting, taking additional account of further categorisation of increased risk of fracture, which may inform choice of therapeutic approach. Methods Clinical perspective and updated literature search. Results The following areas are reviewed: categorisation of fracture risk and general pharmacological management of osteoporosis. Conclusions A platform is provided on which specific guidelines can be developed for national use to characterise fracture risk and direct interventions.
year | journal | country | edition | language |
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2019-11-13 | Osteoporosis International |