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RESEARCH PRODUCT
Pregnancy and periodontal disease: does exist a two-way relationship?
Angelo TagliabueMarco GargariP GavoglioJavier Silvestre-rangilLucia TettamantiM NardoneDorina Lauritanosubject
Maternal mortalitymedicine.medical_specialtyAdverse pregnancy outcomeGingival and periodontal pocketOverviewDentistryInflammationDiseaseReviewDental plaque03 medical and health sciences0302 clinical medicineImmune systemPeriodontal diseasePregnancyInternal medicinemedicineAdverse pregnancy outcome; Maternal mortality; Overview; Perinatal mortality; Periodontal disease; Periodontitis; Pregnancy; Preterm birth; Systematic review; Treatment; Dentistry (all)PeriodontitisGeneral DentistryPerinatal mortalityPeriodontitisPregnancybusiness.industryPeriodontitiMED/28 - MALATTIE ODONTOSTOMATOLOGICHEPreterm birth030206 dentistrymedicine.diseaseTreatmentSystematic reviewDentistry (all)Periodontal diseasemedicine.symptombusiness030215 immunologydescription
Periodontal disease (PD) is an inflammatory disease of the tissues supporting the teeth. PD affects 65 million adults over the age of 30 years in the USA, and worldwide 5 to 70% of adults. Women who develop PD during pregnancy, itâs estimated 1 woman in 5, may have a higher risk of adverse pregnancy outcomes. PD during pregnancy starts by dental plaque and is increased by the action of pregnancy hormones. In order to study the effect of PD on adverse pregnancy outcomes, we have performed this narrative review summarising the current studies about the influence of PD on pregnancy. Periodontal pockets are a reservoir of oral microbiota. Modifications in oral microbiota may be considered as a potential mechanism for developing PD during pregnancy. PD is surely caused by bacteria, but the progression and worsening are due to a host immune response. The inflammation caused by PD is not limited to the oral cavity. It is hypothesized that episodes of bacteraemia and dissemination of endotoxins from periodontal pockets can induce the activation of the systemic immune response. In conclusion our narrative review shows that thereâs no relationship between PD and adverse pregnancy outcomes, and PD treatment during pregnancy does not confer a general protection against adverse pregnancy outcomes
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2017-09-27 |