6533b854fe1ef96bd12af5ff

RESEARCH PRODUCT

Serum inhibin A, inhibin B, pro-alphaC, and activin A levels in women with idiopathic premature ovarian failure.

Michael SchaffrathW MunzKunhard PollowRudolf SeufertWerner SchmidtMohamed Eid Hammadeh

subject

endocrine systemInhibin amedicine.medical_specialtyendocrine system diseasesPrimary Ovarian InsufficiencyAndrologyOvarian functionInternal medicineMedicineHumansInhibinsProtein Precursorsreproductive and urinary physiologyInhibin bPostmenopausal womenbusiness.industryObstetrics and Gynecologyfemale genital diseases and pregnancy complicationsActivin aPostmenopauseIdiopathic premature ovarian failureEndocrinologyReproductive MedicineFemalebusinesshormones hormone substitutes and hormone antagonists

description

Serum inhibin A, inhibin B, pro-alphaC, and activin A levels in 30 women with idiopathic premature ovarian failure (POF), 30 postmenopausal women, and 30 age-matched fertile women were determined. Women with POF showed low levels of inhibin A and inhibin B, but not of activin A, whereas the levels of pro-alphaC were significantly higher than in postmenopausal women. Thus, the circulating level of pro-alphaC could be a marker for assessing residual ovarian function in women with POF.

yearjournalcountryeditionlanguage
2003-07-23Fertility and sterility
10.1016/j.fertnstert.2004.05.065https://pubmed.ncbi.nlm.nih.gov/15374731