6533b855fe1ef96bd12b064b
RESEARCH PRODUCT
Tumour necrosis factor in rheumatoid arthritis and osteoarthritis patients in blood serum and synovial fluid
J. ArajsL. KovalchukE. SikoraI. AsticaI. BulinaJ. ZepaA. SochnevI. JaunalksneD. AndersoneV. Lavrentjevssubject
musculoskeletal diseasesAutoimmune diseasebusiness.industryImmunologyInterleukinmedicine.diseaseGeneral Biochemistry Genetics and Molecular BiologyProinflammatory cytokinePathogenesisBlood serumRheumatologyRheumatoid arthritisImmunologymedicineImmunology and AllergySynovial fluidTumor necrosis factor alphabusinessdescription
Rheumatoid arthritis (RA) is a chronic autoimmune disease of unknown cause which affects the ability of elderly people to work. There is strong evidence to suggest that inflammatory mediators such as tumour necrosis factor α (TNFα) and interleukin 1 (IL1) have a critical role in the pathogenesis of RA. Biological treatment blocks pathological pathways in the actions of these proinflammatory cytokines. The aim of this study was …
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2010-03-01 | Annals of the Rheumatic Diseases |