6533b855fe1ef96bd12b117e
RESEARCH PRODUCT
Effects of a low-power He-Ne laser on the healing of experimental colon anastomoses: our experience
Vicente Garcia-fonsErnesto Molina-andreuJose Vidal-martinezVicente Torres-gilFrancisco Martinez-sorianoR. Perez-sarrioFrancisco Asencio-aranasubject
medicine.medical_specialtymedicine.diagnostic_testbusiness.industryGeneral EngineeringAnastomosisAtomic and Molecular Physics and OpticsColorectal surgerySurgeryEndoscopyColonic obstructionOpticsRepeated dosesAnastomotic leaksmedicineHe ne laserbusinessWound healingdescription
Despite technical advances, the incidence of anastomotic leaks in elective colorectal surgery remains around 14%. Recent studies suggest that the use of low-energy lasers may enhance wound healing in different tissues in a selective, nondestructive manner. Based on these findings we have attempted to provide experimental background on the effects of a He-Ne laser during the early stages of healing in 155 colonic anastomoses performed on rats. The irradiation (external or endoscopical) ofthe anastomoses by repeated doses below 4 J/cm 2 suggest (1) the laser-induced enhancement of anastomotic healing can be obtained in both healthy colons or in situations in which anastomotic breakdown is more likely, such as colonic obstruction; (2) the photochemical effects observed can be transmitted through optic fibers; (3) energy densities above the range of 4 J/cm 2 show no benefit in wound-healing stimulation.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1992-01-01 | Optical Engineering |