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RESEARCH PRODUCT
Pulmonary vascular endothelium: the orchestra conductor in respiratory diseases
Joan Albert BarberàTheodoros P. VassilakopoulosMaria R. BonsignoreMark T. GladwinTom KotsimbosMarc HumbertLaurence DewachterAlice HuertasAlice HuertasUgo TestaLaurent SavaleAnh Tuan Dinh-xuanSunita BhattacharyaChristophe GuignabertChristophe GuignabertMartin R. WilkinsPeter BärtschOlivier SanchezJahar BhattacharyaPeter Dorfmüllersubject
Pulmonary and Respiratory MedicineParismedicine.medical_specialtyEndotheliumRespiratory Tract DiseasesRespiratory SystemDysfunctional familyDiseasePulmonary ArteryVascular Remodeling030204 cardiovascular system & hematologyLung injury03 medical and health sciences0302 clinical medicinemedicineHumansEndothelial dysfunctionIntensive care medicineLungbusiness.industryTranslational medicine11 Medical And Health SciencesCongresses as Topicmedicine.diseasePulmonary hypertensionmedicine.anatomical_structure030228 respiratory systemDrug DesignEndothelium Vascularbusinessdescription
The European Respiratory Society (ERS) Research Seminar entitled “Pulmonary vascular endothelium: orchestra conductor in respiratory diseases - highlights from basic research to therapy” brought together international experts in dysfunctional pulmonary endothelium, from basic science to translational medicine, to discuss several important aspects in acute and chronic lung diseases. This review will briefly sum up the different topics of discussion from this meeting which was held in Paris, France on October 27–28, 2016. It is important to consider that this paper does not address all aspects of endothelial dysfunction but focuses on specific themes such as: 1) the complex role of the pulmonary endothelium in orchestrating the host response in both health and disease (acute lung injury, chronic obstructive pulmonary disease, high-altitude pulmonary oedema and pulmonary hypertension); and 2) the potential value of dysfunctional pulmonary endothelium as a target for innovative therapies.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2017-04-10 | European Respiratory Journal |