Antimykotische wirkstoffe. XIX. 4,6-Disubstituierte 2-(cyanamino)pyrimidine

6533b855fe1ef96bd12b1bd8

RESEARCH PRODUCT

Antimykotische wirkstoffe. XIX. 4,6-Disubstituierte 2-(cyanamino)pyrimidine

subject

Diketone chemistry.chemical_compound chemistry Pyrimidine Stereochemistry Acetylacetone Organic Chemistry Structure type Aliphatic compound Medicinal chemistry

description

Aus der Umsetzung von Dicyandiamid (1) mit β-Diketonen (2a-c) gehen die 2-Cyanaminopyrimidine (3a-c) hervor. Strukturtyp 3 wird durch spektroskopische Daten gestutzt, wahrend gleichzeitig eine 1-Cyan-2-imino-struktur (4) ausgeschlossen wird. Verbindung 3a zeigt fungistatische und nematizide Wirkungen. The reaction of city dicyandiamide (1) with β-diketones 2a-c leads to 2-(cyanoamino)pyrimidines 3a-c. Structure type 3 is supported by spectroscopic data, while at the same time a 1-cyano-2-imino structure (4) is excluded. Compound 3a exhibits fungistatic and nematicidal activity.

year	journal	country	edition	language
1985-05-01	Journal of Heterocyclic Chemistry

https://doi.org/10.1002/jhet.5570220321

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