A phase 1b, dose-finding study of ruxolitinib plus panobinostat in patients with myelofibrosis.

6533b856fe1ef96bd12b248a

RESEARCH PRODUCT

A phase 1b, dose-finding study of ruxolitinib plus panobinostat in patients with myelofibrosis.

Bruno Martino Daniel B. Lipka Thomas Kindler Suddhasatta Acharyya Eibhlin Conneally Vincent Ribrag Florence Binlich Tracy Liu Alessandro M. Vannucchi Francesco Passamonti Florian H. Heidel Song Mu Claire N. Harrison Amjad Hayat Jean-jacques Kiladjian

subject

Cancer Research Ruxolitinib Pathology medicine.medical_specialty business.industry Bone marrow fibrosis medicine.disease chemistry.chemical_compound Dose finding Oncology chemistry Panobinostat Cancer research Medicine In patient business Janus kinase Myelofibrosis Myeloproliferative neoplasm medicine.drug

description

7022^ Background: Myelofibrosis (MF) is a myeloproliferative neoplasm characterized by dysregulation of the Janus kinase (JAK) pathway resulting in bone marrow fibrosis, splenomegaly, and debilitat...

year	journal	country	edition	language
2014-05-20	Journal of Clinical Oncology

https://doi.org/10.1200/jco.2014.32.15_suppl.7022

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