GIPC: Glycosyl Inositol Phospho Ceramides, the major sphingolipids on earth

6533b856fe1ef96bd12b267f

RESEARCH PRODUCT

GIPC: Glycosyl Inositol Phospho Ceramides, the major sphingolipids on earth

Sébastien Mongrand Paul Gouguet Véronique Germain Julien Gronnier Jean-luc Cacas

subject

0106 biological sciences 0301 basic medicine Glycosylation Glycosylation Very long chain fatty acid Plant Science Biology Ceramides Models Biological 01 natural sciences Cell wall 03 medical and health sciences chemistry.chemical_compound Membrane Microdomains Plant defense against herbivory Animals Glycosyl Inositol Lipid bilayer Sphingolipids Mini-Review Plants Sphingolipid 030104 developmental biology chemistry Biochemistry lipids (amino acids peptides and proteins)010606 plant biology & botany

description

What are the most abundant sphingolipids on earth? The answer is Glycosyl Inositol Phosphoryl Ceramides (GIPCs) present in fungi and the green lineage. In this review, we discuss the putative role of plant GIPCs in the lipid bilayer asymmetry, in the lateral organization of membrane rafts and in the very long chain fatty acid inter-leaflet coupling of lipids in the plant plasma membrane (PM). A special focus on the structural similarities -and putative functions- of GIPCs is discussed by comparison with animal gangliosides, structural homologs of plant GIPCs.

year	journal	country	edition	language
2016-04-13	Plant Signaling & Behavior

https://doi.org/10.1080/15592324.2016.1152438

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