6533b856fe1ef96bd12b26d3

RESEARCH PRODUCT

Importance of selenium status in patients with chronic heart failure

Stephan Von HaehlingJochen SpringerSabine Genth-zotzGabor FoldesRakesh SharmaWolfram DoehnerEwa A. JankowskaKostja RenkoLutz SchomburgStefan D. AnkerNicole Ebner

subject

Lipopolysaccharidebusiness.industrymedicine.medical_treatmentchemistry.chemical_elementmedicine.diseasePathophysiologychemistry.chemical_compoundImmune systemchemistryHeart failureImmunologyMedicineIn patientlcsh:Qbusinesslcsh:Sciencelcsh:Science (General)SeleniumDesensitization (medicine)lcsh:Q1-390

description

Abstract Overactivity of the immune system may be a worthwhile therapeutic target for implementing prognostic improvements. Therefore the impact of lipopolysaccharide (LPS) desensitization on survival may help in the development of novel therapies. An understanding of the pathophysiology of the trace element selenium may complement such approaches, as recent data suggest that inflammatory responses are selenium-dependent.

10.1016/j.pisc.2014.11.022http://dx.doi.org/10.1016/j.pisc.2014.11.022