6533b856fe1ef96bd12b276c
RESEARCH PRODUCT
Next-generation biological control
Eveline C. VerhulstLouis Van De ZandeAlejandra CenturiónKelley LeungLeo W. BeukeboomAlberto UrbanejaJacques BrodeurDirk BabendreierMarcel DickeJohn H. WerrenAngeliki PaspatiSara MagalhãesMilena Chinchilla-ramírezManolis LyrakisJoel González-cabreraSophie R. ChattingtonAndra ThielPanagiota KoskiniotiPanagiota KoskiniotiErica RasKostas BourtzisMargreet A. BruinsBart A. PannebakkerWouter N. PlouvierSophie Le HesranSimone AriënsChristian SchlöttererJudith M. StahlJudith M. StahlNina E. FatourosTim HayePiter BijmaMeritxell Pérez-hedoThomas GrootKim B. FergusonBas J. ZwaanMarkus KnappShuwen XiaLouise E. M. VetSander Vissersubject
0106 biological sciencesProteomicsH10 Pests of plantsInternationalityComputer science[SDV]Life Sciences [q-bio]Laboratory of VirologySequence assemblybiological controlmicrobiome01 natural sciencesGenome editinggeneticsNagoya ProtocolLaboratory of EntomologyCYTOPLASMIC INCOMPATIBILITY2. Zero hunger0303 health sciencesQUANTITATIVE TRAIT LOCICommercefood and beveragesCONTROL AGENTSPE&RCBiosystematiekNASONIA-VITRIPENNISGUT CONTENT-ANALYSIS[SDE]Environmental SciencesTraitinsect breedingAXYRIDIS COLEOPTERA-COCCINELLIDAEOriginal ArticleLaboratory of GeneticsLIFE-HISTORY TRAITSGeneral Agricultural and Biological SciencesGenomicsContext (language use)Computational biology[SDV.BID]Life Sciences [q-bio]/Biodiversityartificial selectionQuantitative trait locusAnimal Breeding and GenomicsLaboratorium voor Erfelijkheidsleer010603 evolutionary biologyGeneral Biochemistry Genetics and Molecular BiologyLaboratorium voor Virologiemodelling03 medical and health sciencesgenomics[SDV.BV]Life Sciences [q-bio]/Vegetal BiologyFokkerij en GenomicaPARASITOID WASPSelection (genetic algorithm)modelling.030304 developmental biologySEX DETERMINATIONOriginal ArticlesLaboratorium voor EntomologieWIASgenome assemblyBiosystematicsEPSartificial selection biological control genetics genome assembly genomics insect breeding microbiome modellingdescription
Biological control is widely successful at controlling pests, but effective biocontrol agents are now more difficult to import from countries of origin due to more restrictive international trade laws (the Nagoya Protocol). Coupled with increasing demand, the efficacy of existing and new biocontrol agents needs to be improved with genetic and genomic approaches. Although they have been underutilised in the past, application of genetic and genomic techniques is becoming more feasible from both technological and economic perspectives. We review current methods and provide a framework for using them. First, it is necessary to identify which biocontrol trait to select and in what direction. Next, the genes or markers linked to these traits need be determined, including how to implement this information into a selective breeding program. Choosing a trait can be assisted by modelling to account for the proper agro-ecological context, and by knowing which traits have sufficiently high heritability values. We provide guidelines for designing genomic strategies in biocontrol programs, which depend on the organism, budget, and desired objective. Genomic approaches start with genome sequencing and assembly. We provide a guide for deciding the most successful sequencing strategy for biocontrol agents. Gene discovery involves quantitative trait loci analyses, transcriptomic and proteomic studies, and gene editing. Improving biocontrol practices includes marker-assisted selection, genomic selection and microbiome manipulation of biocontrol agents, and monitoring for genetic variation during rearing and post-release. We conclude by identifying the most promising applications of genetic and genomic methods to improve biological control efficacy
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2020-12-01 | Biological Reviews |