Hemostatic, inflammatory, and oxidative markers in pesticide user farmers

6533b856fe1ef96bd12b3248

RESEARCH PRODUCT

Hemostatic, inflammatory, and oxidative markers in pesticide user farmers

Bouchra Loukidi Sid Ahmed Merzouk Merzouk Hafida Katia Taouli Michel Narce Fatima Zohra Madani

subject

Male 0301 basic medicine Antioxidant Health Toxicology and Mutagenesis medicine.medical_treatment [ SDV.TOX ] Life Sciences [q-bio]/Toxicology Clinical Biochemistry Physiology Ascorbic Acid Metribuzin 010501 environmental sciences medicine.disease_cause 01 natural sciences Biochemistry Hemostatics Protein Carbonylation chemistry.chemical_compound Organophosphate Superoxides immune system diseases Malondialdehyde Surveys and Questionnaires Vitamin E oxidative stress Stresspersistent organic pollutants Lymphocytes Farmers biology Persistent organic pollutants food and beverages Middle Aged Catalase Malondialdehyde Glutathione C-Reactive Protein Catalase Malathion Prothrombin Oxidation-Reduction Research Article Adult Agricultural Health Stress Exposure Superoxide dismutase 03 medical and health sciences Occupational Exposure medicine Humans Pesticides pesticide thrombosis 0105 earth and related environmental sciences Superoxide Dismutase business.industry Vitamin E Fibrinogen [ SDV.BIO ] Life Sciences [q-bio]/Biotechnology Pesticide Ascorbic acid respiratory tract diseases Biotechnology Logistic Models 030104 developmental biology chemistry inflammation In-Vitro Susceptibility biology.protein business Biomarkers Oxidative stress

description

Research Article; International audience; The aim of this work was to investigate inflammatory, oxidative, and thrombotic parameters as biomarkers in farmers exposed to pesticides. Fifty farmers using chemical pesticides and 60 unexposed control men participated in this study. The Mediterranean diet compliance, the duration of pesticide use, and personal protection for pesticides handling were recorded using self-administered questionnaires. Serum biochemical parameters, oxidant/antioxidant, inflammatory, and thrombosis markers were determined. Our findings showed oxidative stress reflected by an increase in malondialdehyde, carbonyl proteins and superoxide anion levels and a decrease in vitamins C and E, glutathione, catalase, and superoxide dismutase activities in farmers. Serum C-reactive protein, prothrombin, and fibrinogen levels were enhanced in these farmers. In conclusion, inflammation, oxidative stress, and metabolic perturbations reflected the possibility of the effects of pesticides to farmers.

year	journal	country	edition	language
2016-02-17	Biomarkers

https://doi.org/10.3109/1354750x.2015.1118545