6533b857fe1ef96bd12b3a8e

RESEARCH PRODUCT

Adverse Effects of Nonsteroidal Anti-Inflammatory Drugs on the Small and Large Bowel

Null SchneiderNull BenzNull BeermannNull SchiebelerNull Riemann

subject

medicine.medical_specialtymedicine.drug_classBiopsydigestive systemGastroenterologyEndoscopy GastrointestinalAnti-inflammatorychemistry.chemical_compoundInternal medicineIntestine SmallmedicineHumansUpper gastrointestinalLarge intestineIntestine LargeIntestinal MucosaAdverse effectUlcerNonsteroidalbusiness.industryAnti-Inflammatory Agents Non-SteroidalGastroenterologydigestive system diseasesSmall intestineIntestinal Diseasesmedicine.anatomical_structurechemistryDuodenumbusinessComplication

description

Nonsteroidal anti-inflammatory drugs (NSAID) account for a large part of prescriptions and self-administered medication worldwide. The adverse effects on the upper gastrointestinal tract are well documented. However, in an increasing number of publications adverse effects in the small and large intestine distal to the duodenum are being reported. This paper provides an updated review of current as well as earlier literature on the pathogenesis of such adverse effects and the potential damage to the small and large bowel caused by NSAID. In addition, suggestions for an appropriate diagnostic workup of NSAID damage are discussed.

yearjournalcountryeditionlanguage
1999-12-22Endoscopy
https://doi.org/10.1055/s-1999-75