Performance of the Medical Research Council (MRC) and the Leukemia Research Foundation (LRF) score in predicting survival benefit with hypomethylating agent use in patients with relapsed or refractory acute myeloid leukemia

6533b857fe1ef96bd12b4f13

RESEARCH PRODUCT

Performance of the Medical Research Council (MRC) and the Leukemia Research Foundation (LRF) score in predicting survival benefit with hypomethylating agent use in patients with relapsed or refractory acute myeloid leukemia

John Barnard Aref Al-kali Vey Norbert Ellen K. Ritchie Mark R. Litzow Pau Montesinos Ulrich Germing Amer M. Zeidan Mikkael A. Sekeres Thomas Cluzeau Rami S. Komrokji Juan Bergua Nikolai A. Podoltsev Raphael Itzykson Thomas Prebet Josefina Serrano Vivek Verma Tae Kon Kim Pierre Fenaux Amir T. Fathi Sarah Perreault Steven D. Gore Maximilian Stahl Valeria Santini Michelle Deveaux Andrew M. Brunner Gail J. Roboz Vijaya Raj Bhatt

subject

Adult Male Oncology Cancer Research medicine.medical_specialty Myeloid Adolescent endocrine system diseases medicine.medical_treatment Hematopoietic stem cell transplantation Risk Assessment Young Adult Risk Factors hemic and lymphatic diseases Internal medicine Antineoplastic Combined Chemotherapy Protocols medicine Humans Transplantation Homologous neoplasms Survival analysis Aged Retrospective Studies Aged 80 and over business.industry Hematopoietic Stem Cell Transplantation Myeloid leukemia Hematology Middle Aged Prognosis medicine.disease Survival Analysis Transplantation Leukemia Myeloid Acute Leukemia Treatment Outcome medicine.anatomical_structure Oncology Tolerability Hypomethylating agent Drug Resistance Neoplasm hypomethylating agent acute myeloid leukemia.Female Neoplasm Recurrence Local business

description

Patients with primary refractory or relapsed-acute myeloid leukemia (RR-AML), particularly older adults, have dismal outcomes and limited therapy options [1]. Given the tolerability of hypomethylat...

year	journal	country	edition	language
2018-07-02	Leukemia & Lymphoma

https://doi.org/10.1080/10428194.2018.1468893

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