6533b857fe1ef96bd12b5062
RESEARCH PRODUCT
The use of emergency laparoscopy for acute abdomen in the elderly: the FRAILESEL Italian Multicenter Prospective Cohort Study
Gianluca CostaPietro FransveaMauro PoddaAdolfo PisanuFrancesco Maria CarranoAngelo IossaGenoveffa Balducci AgrestaF Ferdinando Collaborative Study Group: AgrestaG AlemannoG AnaniaM AntropoliG ArgenioJ AtzeniN AveniaA AzzinnaroG BaldazziG BalducciG BarberaG BellanovaC BergaminiL BersigottiPp BianchiC BombardiniG BorzellinoS BozzoG BrachiniGm BuonannoT CaniniS CardellaG CarraraD CassiniM CastriconiG CeccarelliD CeliM CeresoliM ChiarugiN CillaraF CiminoL CobuccioG CocorulloE ColangeloG CostaA CrucittiP Dalla CanevaM De LucaA De Manzoni GarberiniC De NiscoM De PrizioA De SolA DibellaT FalcioniN FalcoC FarinaE FinottiT FontanaG FrancioniP FransveaB FrezzaG GarulliM GennaS GiannessiA GioffrèA GiordanoD GozzoS GrimaldiG GulottaV IacopiniT IarussiE LaterzaA LeonardiL LepreL LorenzonG LuridianaA MalagninoG MarP MariniR MarzaioliG MassaV MecarelliA MingoliG NigriS OcchionorelliN PadernoGm PaliniD ParadiesM ParoliF PerroneL PetruzzelliA PezzollaD PiazzaV PiazzaM PiccoliA PisanuM PoddaG PoillucciR PorfidiaG RossiP RuscelliA SpagnoliR SulisD TartagliaC TranàA TravaglinoP TomaiuoloA ValeriG VasquezM ZagoE. Zanonisubject
MaleSettore MED/18 - CHIRURGIA GENERALEEndoscopy GastrointestinalCohort Studies0302 clinical medicinePostoperative ComplicationsElderlyAbdomen80 and overMedicineProspective StudiesProspective cohort studyLaparoscopyAbdomen AcuteAged 80 and overmedicine.diagnostic_testMortality rateAge FactorsPrognosisMulticenter studyItalyAcute abdomen030220 oncology & carcinogenesisEmergency surgery030211 gastroenterology & hepatologyFemalemedicine.symptomCohort studyRiskGastrointestinalmedicine.medical_specialtyAcuteMalignancyNOAcute abdomen03 medical and health sciencesEmergency surgeryHumansAgedbusiness.industryacute abdomen; elderly; emergency surgery; laparoscopy; multicenter studyEndoscopymedicine.diseaseSurgerySurgeryLaparoscopyEmergenciesMorbiditybusinessProcedures and Techniques UtilizationAbdominal surgerydescription
As the world population is aging rapidly, emergency abdominal surgery for acute abdomen in the elderly represents a global issue, both in developed and developing countries. Data regarding all the elderly patients who underwent emergency abdominal surgery from January 2017 to December 2017 at 36 Italian surgical departments were analyzed with the aim to appraise the contemporary reality regarding the use of emergency laparoscopy for acute abdomen in the elderly. 1993 patients were enrolled. 1369 (68.7%) patients were operated with an open technique; whereas, 624 (31.3%) underwent a laparoscopic operation. The postoperative morbidity rate was 32.6%, with a statically significant difference between the open and the laparoscopic groups (36.2% versus 22.1%, p < 0.001). The reported mortality rate was 8.8%, with a statistically significant difference between the open and the laparoscopic groups (11.2% versus 2.2%, p < 0.001). Our results demonstrated that patients in the ASA II (58.1%), ASA III (68.7%) and ASA IV (88.5%) groups were operated with the traditional open technique in most of the cases. Only a small percentage of patients underwent laparoscopy for perforated gastro-duodenal ulcer repair (18.9%), adhesiolyses with/without small bowel resection (12.2%), and large bowel resection (10.7%). Conversion to open technique was associated with a higher mortality rate (11.1% versus 2.2%, p < 0.001) and overall morbidity (38.9% versus 22.1%, p = 0.001) compared with patients who did not undergo conversion. High creatinine (p < 0.001) and glycaemia (p = 0.006) levels, low hemoglobin levels (p < 0.001), oral anticoagulation therapy (p = 0.001), acute respiratory failure (p < 0.001), presence of malignancy (p = 0.001), SIRS (p < 0.001) and open surgical approach (p < 0.001) were associated with an increased risk of postoperative morbidity. Regardless of technical progress, elderly patients undergoing emergency surgery are at very high risk for in-hospital complications. A detailed analysis of complications and mortality in the present study showed that almost 9% of elderly patients died after surgery for acute abdomen, and over 32% developed complications.
year | journal | country | edition | language |
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2020-01-01 |