6533b857fe1ef96bd12b5093

RESEARCH PRODUCT

Comparison of complex fractionated atrial electrograms at cellular scale using numerical and experimental models.

Sabir JacquirNicolas NavoretBinbin XuStéphane Binczak

subject

PhysicsScale (ratio)Experimental modelModels CardiovascularAction PotentialsNumerical modelsCellular levelElectrocardiographyBiological ClocksHeart Conduction SystemAtrial FibrillationAnimalsHumansComputer SimulationMyocytes CardiacHeart AtriaBiological systemCellular biophysicsBiomedical engineering

description

This study investigates the existence of the pseudo complex fractionated atrial electrogram (CFAE) at cellular level. Our assumptions are based on the fact that CFAEs are linked to the generation of the spiral waves. These are created using a numerical model and an experimental model of in vitro culture of neonatal rats cardiac cells. Pseudo bipolar electrograms resulting from these two models are compared qualitatively and some patterns could be identified as CFAE signature.

yearjournalcountryeditionlanguage
2010-11-25Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
10.1109/iembs.2010.5627235https://pubmed.ncbi.nlm.nih.gov/21096606