6533b858fe1ef96bd12b5720

RESEARCH PRODUCT

Development of micro-contact printing of osteosarcoma cells using MeV ion beam lithography

Sergey GorelickVarpu MarjomäkiSomjai SangyuenyongpipatA.r. Ananda SagariTimo SajavaaraMikko LaitinenHarry J. WhitlowStiina Ikonen

subject

Nuclear and High Energy PhysicsMaterials scienceApertureMicrocontact printingNanotechnologyIon beam lithographyInstrumentationSignalCastingLithographyProton beam writing

description

Abstract For investigation of spatial effects in signalling between cells and also signal substances that trigger cell proliferation and behaviour we are developing a micro Contact Printing process ( μ CP ) . In order to allow printing of cells stamps with high aspect ratio are required and these have been fabricated using Programmed Proximity Aperture Lithography (PPAL) with 3 MeV 4 He 2 + ions to produce PMMA masters for casting the stamps in PDMS. A simple printing device was developed and the first results using this to print human osteosarcoma cells is demonstrated.

https://doi.org/10.1016/j.nimb.2009.03.018