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RESEARCH PRODUCT
A cross-sectional survey among patients and prescribers on insulin dosing irregularities and impact of mild (self-treated) hypoglycemia episodes in Spanish patients with type 2 diabetes as compared to other European patients.
Manuel GalánMeryl BrodFrancisco Javier Ampudia-blascosubject
AdultMalemedicine.medical_specialtyCross-sectional studyEndocrinology Diabetes and Metabolismmedicine.medical_treatmentHealth PersonnelType 2 diabetesHypoglycemiaSeverity of Illness IndexMedication AdherenceEndocrinologyQuality of lifeDiabetes managementInternal medicineDiabetes mellitusSurveys and QuestionnairesmedicineHumansHypoglycemic AgentsInsulinDosingAgedAged 80 and overbusiness.industryInsulinMiddle Agedmedicine.diseaseHypoglycemiaSurgeryEuropeSelf CareCross-Sectional StudiesDiabetes Mellitus Type 2SpainFemalebusinessdescription
In Spain, data suggest that 13.8% of adults have diabetes. Two important aspects in diabetes management are mild hypoglycemic episodes and poor treatment adherence. This study assesses the impact of missed insulin doses and prevalence of mistimed and reduced insulin doses and mild hypoglycemia in patients with type 2 diabetes treated with basal insulin analogues in Spain, and compares the data collected to pooled data from 8 other European countries (OECs).GAPP2 was an international, online, cross-sectional study of diabetic patients aged ≥40 years treated with long-acting insulin analogues and their healthcare professionals. Patients and healthcare professionals were recruited from online research panels. Data reported in Spain are compared to pooled data from 8 OECs.In Spain, 1-3% of patients reported they had reduced, missed, or mistimed at least one insulin does in the previous month. Significantly more OEC patients reported dosing irregularities (15-23%; all P0.01). In Spain, 77% of patients were worried and 59% felt guilty for missing a dose of basal insulin, while 24% reported that they were very worried about nocturnal hypoglycemia. Significantly fewer OEC patients reported worrying (47%; P0.01) and feeling guilty (37%; P0.01) about missing an insulin dose, or worry about nocturnal hypoglycemia (12%; P0.01).In Spain, patients with type 2 diabetes report fewer dosing irregularities and hypoglycemic episodes as compared to patients from OECs. However, Spanish patients appear to have a reduced quality of life related to hypoglycemia as well as worry and guilt related to insulin dosing irregularities.
year | journal | country | edition | language |
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2014-10-01 | Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion |