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RESEARCH PRODUCT

Eye Movement Involvement in Parry-Romberg Syndrome: A Clinicopathologic Case Report

A. CordeyH. H. GoebelA. A. Zubcov-iwantscheffM. Bacharach-buhlesCris S. ConstantinescuF. ThömkeIrene Gottlob

subject

AdultEye Movementsgenetic structuresExtraocular musclesOcular Motility DisordersOcular Motility DisordersFacial HemiatrophyDiplopiamedicineHumansMuscle biopsymedicine.diagnostic_testbusiness.industryEnophthalmosMedial rectus muscleEye movementParry–Romberg syndromeAnatomymedicine.diseaseFibrosiseye diseasesOphthalmologyOculomotor Musclemedicine.anatomical_structureOculomotor MusclesFemalesense organsmedicine.symptombusiness

description

We report the case of a 38-year-old woman who developed a progressive bilateral disease in which the eye motility disorder-diplopia-is the outstanding feature over a period of 12 years. The muscle biopsy of the medial rectus muscle did not show any trace of striated muscle. To the best of our knowledge, this is the first pathological report in an affected extraocular muscle of a patient with Parry-Romberg syndrome (PRS). Previous rare reports of diplopia in PRS have been attributed to enophthalmos, progressive atrophy of the orbit, ocular motor nerve dysfunction, or mechanical restrictions.

https://doi.org/10.1080/09273970802240874