6533b858fe1ef96bd12b5a63

RESEARCH PRODUCT

DMPP and the adrenergic nerve terminal: mechanisms of noradrenaline release from vesicular and extravesicular compartments.

H. J. HolbachKonrad LöffelholzR. Lindmar

subject

PharmacologyNeuronsmedicine.medical_specialtySympathetic Nervous SystemChemistryMyocardiumPharmacology toxicologyAdrenergicMyocardium metabolismHeartGeneral MedicinePharmacologyIn Vitro TechniquesPiperazinesNorepinephrineEndocrinologyInternal medicinemedicineAnimalsNorepinephrine metabolismRabbitsDimethylphenylpiperazinium Iodide

description

DMPP (1,1-dimethyl-4-phenylpiperazine) in various concentrations between 1.6×10−6 M and 6.2×10−5 M was infused into isolated rabbit hearts to study the neuronal release and uptake of noradrenaline.

10.1007/bf00505043https://pubmed.ncbi.nlm.nih.gov/593434