6533b858fe1ef96bd12b611a

RESEARCH PRODUCT

Untersuchungen zur Bedeutung der Frühsommer-Meningoenzephalitis in Rheinland-Pfalz

Vogt MSüss JSchrader CWoessner RBussmann HTreib JPietsch M

subject

Ixodes ricinusbiologymedicine.diagnostic_testbusiness.industryPublic Health Environmental and Occupational HealthTick-borne encephalitismedicine.diseasebiology.organism_classificationVirologyNeutralizationVirusVaccinationImmunoassayImmunologymedicineViral diseasebusinessMeningitis

description

Within the scope of a prospective clinical study during 2001 in Rhineland-Palatinate specimen from sera and cerebrospinal fluids of 163 patients with suspected meningitis were controlled in an enzyme immunoassay concerning a TBE infection. Questionable results were checked via a neutralisation test. In no case such an infection was confirmed. No virus specific nucleic acids could be detected in 998 nymphs and adults of Ixodes ricinus in an additional investigation in 2000. Therefore Rhineland-Palatinate has to be considered as a region with low virus prevalence. A general recommendation for vaccination is not necessary.

https://doi.org/10.1055/s-2002-34616