6533b858fe1ef96bd12b6237

RESEARCH PRODUCT

Cephalosporin resistantEscherichia colifrom cancer patients in Cairo, Egypt

Mohammed O. AbdelazizCinzia CalàCaterina MamminaAurora AleoCelestino BonuraTeresa Fasciana

subject

medicine.drug_classImmunologyCephalosporinCancerBiologymedicine.disease_causemedicine.diseaseMicrobiologyVirologyMicrobiologyMultiple drug resistanceVirologymedicineEscherichia coli

description

Cephalosporin-resistant Escherichia coli has been increasingly reported worldwide. In this study, 32 cephalosporin resistant E. coli isolates identified from cancer patients in Cairo, Egypt in 2009–2010 were analyzed. Twenty-three were of phylogenetic group D, seven A and one each B1 and B2. By rep-PCR 15 phylogroup D isolates were grouped in four clusters, one with sequence type (ST) 405 and three ST68. Seventeen isolates showed single patterns. blaCTX-M-15 and aac(6')-Ib-cr were the most common resistance determinants. blaOXA-48 and blaVIM were also detected. Multidrug resistant E. coli seriously affects healthcare, especially in immunocompromised hosts, such as cancer patients.

yearjournalcountryeditionlanguage
2013-05-01Microbiology and Immunology
https://doi.org/10.1111/1348-0421.12046